In the past 15 years, B cells have been rediscovered to be not merely bystanders but rather
active participants in autoimmune aetiology. This has been fuelled in part by the clinical …

Pemphigus is a group of IgG-mediated autoimmune diseases of stratified squamous
epithelia, such as the skin and oral mucosa, in which acantholysis (the loss of cell adhesion) …

Background Pemphigus encompasses a group of life‐threatening autoimmune bullous
diseases characterized by blisters and erosions of the mucous membranes and skin. Before …

Background High doses of corticosteroids are considered the standard treatment for
pemphigus. Because long-term corticosteroid treatment can cause severe and even life …

Pemphigus encompasses a heterogeneous group of autoimmune blistering diseases, which
affect both mucous membranes and the skin. The disease usually runs a chronic-relapsing …

Success with B cell depletion using rituximab has proven the concept that B lineage cells
represent a valid target for the treatment of autoimmune diseases, and has promoted the …

Pemphigus vulgaris is a chronic autoimmune bullous dermatosis that results from the
production of autoantibodies against desmogleins 1 and 3. It is the most frequent and most …

Pemphigus and bullous pemphigoid are autoantibody-mediated blistering skin diseases. In
pemphigus, keratinocytes in epidermis and mucous membranes lose cell-cell adhesion, and …

British Association of Dermatologists’ guidelines for the management of pemphigus vulgaris
2017 | British Journal of Dermatology | Oxford Academic Skip to Main Content Advertisement …

Background Pemphigus encompasses a group of life‐threatening autoimmune bullous
diseases characterized by blisters and erosions of the mucous membranes and skin. Before …