In the area of asymmetric organocatalysis, significant effort has been dedicated during the
last decade to improve the performance of emblematic catalysts such as proline, as well as …

Catalytic asymmetric reduction of prochiral ketones with hydrides such as boranes and
borohydrides is one of the simplest and the most convenient methods for obtaining chiral …

The preparation of optically pure secondary alcohols in the presence of catalysts based on
chiral ligands derived from monoterpenes, such as pinenes, limonenes and carenes, is …

Novel chiral N-heterocyclic carbenes derived from (−)-β-pinene have been synthesized and
used as efficient catalysts for the intramolecular Stetter reaction. Mono-, di-, and …

(+)-Nopinone, prepared from naturally occurring (−)-β-pinene, was converted to the two
regioisomeric amino alcohols 3-MAP and 2-MAP in very good yield and excellent isomeric …

A simple one‐pot three‐step synthetic route towards chiral γ‐amino alcohols has been
established. Considering the overall stereocontrol of the synthetic protocol, the first and key …

A one‐pot synthesis of fluorinated chiral alcohols from α‐bromoarylketones and
fluoroalcohols is described. The fluorinated ketone intermediates were formed from α …

Water-soluble ligands (R, R)-2 were successfully prepared, in which the bis-meta-
sulphonated ligand was definitely detected as the major product. The corresponding …

As part of medicinal chemistry efforts we found it necessary to develop general syntheses of
highly enantiomerically enriched 1-aryl-2-chloroethanols and 1-aryl-2-methylaminoethanols …

N-Heterocyclic carbenes and their metal complexes have found applications in many
organic transformations. Apart from the privileged C 2-symmetry present in modern …