Modulating ROS to overcome multidrug resistance in cancer

Q Cui, JQ Wang, YG Assaraf, L Ren, P Gupta… - Drug Resistance …, 2018 - Elsevier
The successful treatment of cancer has significantly improved as a result of targeted therapy
and immunotherapy. However, during chemotherapy, cancer cells evolve and can acquire …

An overview of the evidence and mechanisms of herb–drug interactions

PS Fasinu, PJ Bouic, B Rosenkranz - Frontiers in pharmacology, 2012 - frontiersin.org
Despite the lack of sufficient information on the safety of herbal products, their use as
alternative and/or complementary medicine is globally popular. There is also an increasing …

[PDF][PDF] 中药质量标志物(Q-Marker): 中药产品质量控制的新概念

刘昌孝, 陈士林, 肖小河, 张铁军, 侯文彬, 廖茂梁 - 中草药, 2016 - tiprpress.com
为促进中医药产业健康发展, 完善质量标准体系, 健全以《 中国药典》 为核心的国家药品标准体系
, 提升中药及产品质量标准, 在研究现有质量评价与控制方法及存在问题的基础上 …

Ameliorating effects of compounds derived from Salvia miltiorrhiza root extract on microcirculatory disturbance and target organ injury by ischemia and reperfusion

JY Han, JY Fan, Y Horie, S Miura, DH Cui… - Pharmacology & …, 2008 - Elsevier
Ischemia and reperfusion (I/R) exerts multiple insults in microcirculation, frequently
accompanied by endothelial cell injury, enhanced adhesion of leukocytes, macromolecular …

A high‐quality reference genome sequence of Salvia miltiorrhiza provides insights into tanshinone synthesis in its red rhizomes

Z Song, C Lin, P Xing, Y Fen, H Jin, C Zhou… - The Plant …, 2020 - Wiley Online Library
Salvia miltiorrhiza Bunge, also known as red sage or Danshen, is an important traditional
Chinese medicine (TCM) that has been used for thousands of years to treat cardiovascular …

SmMYB36, a Novel R2R3-MYB Transcription Factor, Enhances Tanshinone Accumulation and Decreases Phenolic Acid Content in Salvia miltiorrhiza Hairy Roots

K Ding, T Pei, Z Bai, Y Jia, P Ma, Z Liang - Scientific Reports, 2017 - nature.com
Phenolic acids and tanshinones are two major bioactive components in Salvia miltiorrhiza
Bunge. A novel endogenous R2R3-MYB transcription factor, SmMYB36, was identified in …

Advancement in analysis of Salviae miltiorrhizae Radix et Rhizoma (Danshen)

YG Li, L Song, M Liu, ZT Wang - Journal of chromatography A, 2009 - Elsevier
This review summarizes the recent advances in the chemical analysis of Danshen and its
finished products, including the introduction of the identified bioactive components …

Quality transitivity and traceability system of herbal medicine products based on quality markers

C Liu, D Guo, L Liu - Phytomedicine, 2018 - Elsevier
Background Due to a variety of factors to affect the herb quality, the existing quality
management model is unable to evaluate the process control. The development of the …

JA-Responsive Transcription Factor SmMYB97 Promotes Phenolic Acid and Tanshinone Accumulation in Salvia miltiorrhiza

L Li, D Wang, L Zhou, X Yu, X Yan… - Journal of Agricultural …, 2020 - ACS Publications
Phenolic acids and tanshinones are active principles in Salvia miltiorrhiza Bunge
administered for cardiovascular and cerebrovascular diseases. Jasmonic acid (JA) …

Overexpression of SmbHLH10 enhances tanshinones biosynthesis in Salvia miltiorrhiza hairy roots

B Xing, D Yang, H Yu, B Zhang, K Yan, X Zhang, R Han… - Plant science, 2018 - Elsevier
The bHLH transcription factors have important role in regulation of plant growth,
development, and secondary metabolism. Tanshinones are the major pharmaceutical …