Present and future of metal nanoparticles in tumor ablation therapy

W Lou, L Xie, L Xu, M Xu, F Xu, Q Zhao, T Jiang - Nanoscale, 2023 - pubs.rsc.org
Cancer is an important factor affecting the quality of human life as well as causing death.
Tumor ablation therapy is a minimally invasive local treatment modality with unique …

Concepts and capabilities of in-house built nanosecond pulsed electric field (nsPEF) generators for electroporation: State of art

P Butkus, A Murauskas, S Tolvaišienė, V Novickij - Applied Sciences, 2020 - mdpi.com
Electroporation is a pulsed electric field triggered phenomenon of cell permeabilization,
which is extensively used in biomedical and biotechnological context. There is a growing …

Characterization of conductivity changes during high-frequency irreversible electroporation for treatment planning

Y Zhao, S Bhonsle, S Dong, Y Lv, H Liu… - IEEE Transactions …, 2017 - ieeexplore.ieee.org
For irreversible-electroporation (IRE)-based therapies, the underlying electric field
distribution in the target tissue is influenced by the electroporation-induced conductivity …

First human trial of high-frequency irreversible electroporation therapy for prostate cancer

S Dong, H Wang, Y Zhao, Y Sun… - Technology in cancer …, 2018 - journals.sagepub.com
Irreversible electroporation, as a nonthermal therapy of prostate cancer, has been used in
clinic for several years. The mechanism of irreversible electroporation ablation is thermal …

Bipolar microsecond pulses and insulated needle electrodes for reducing muscle contractions during irreversible electroporation

C Yao, S Dong, Y Zhao, Y Lv, H Liu… - IEEE Transactions …, 2017 - ieeexplore.ieee.org
Objective: To minimize the effect of muscle contractions during irreversible electroporation
(IRE), this paper attempts to research the ablation effect and muscle contractions by …

Effects of external electric fields on double proton transfer kinetics in the formic acid dimer

AA Arabi, CF Matta - Physical Chemistry Chemical Physics, 2011 - pubs.rsc.org
Molecules can be exposed to strong local electric fields of the order of 108–1010 V m− 1 in
the biological milieu. The effects of such fields on the rate constant (k) of a model reaction …

A novel high-frequency bipolar pulsed power generator for biological applications

W Zeng, L Yu, S Dong, J Ma, Y Wang… - … on Power Electronics, 2020 - ieeexplore.ieee.org
High-frequency bipolar high-voltage pulsed electric field can be used in tumor ablation to
uniform the electric field distribution in the ablated region and inhibit muscle contraction …

FPGA-controlled all-solid-state nanosecond pulse generator for biological applications

C Yao, X Zhang, F Guo, S Dong, Y Mi… - IEEE Transactions on …, 2012 - ieeexplore.ieee.org
In vivo studies of tumor-cell apoptosis induced by nanosecond pulsed electric field require
high-voltage nanosecond pulses delivered to the biological tissues. In this paper, a newly …

Ablation outcome of irreversible electroporation on potato monitored by impedance spectrum under multi-electrode system

Y Zhao, H Liu, SP Bhonsle, Y Wang… - Biomedical engineering …, 2018 - Springer
Background Irreversible electroporation (IRE) therapy relies on pulsed electric fields to non-
thermally ablate cancerous tissue. Methods for evaluating IRE ablation in situ are critical to …

Development of a multi-pulse conductivity model for liver tissue treated with pulsed electric fields

Y Zhao, S Zheng, N Beitel-White, H Liu… - … in Bioengineering and …, 2020 - frontiersin.org
Pulsed electric field treatment modalities typically utilize multiple pulses to permeabilize
biological tissue. This electroporation process induces conductivity changes in the tissue …