Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality for
patients with type 2 diabetes, despite recent significant advances in management strategies …

Nephrotic syndrome results in hyperlipidemia and profound alterations in lipid and
lipoprotein metabolism. Serum cholesterol, triglycerides, apolipoprotein B (apoB) …

Outcome and risk factors of ischemic heart disease in chronic uremia. To determine the
prognosis and risk factors for ischemic heart disease in chronic uremia, a cohort of 432 …

The incidence of cardiovascular disease (CVD) is very high in patients with chronic kidney
(CKD) disease and in kidney transplant recipients. Indeed, available evidence for these …

Hyperlipidemia so commonly complicates heavy proteinuria that it has come to be regarded
as an integral feature of the nephrotic syndrome (NS). Characteristically, total plasma …

Cardiomyopathy in chronic uremia results from pressure and volume overload. The former
causes concentric left ventricular (LV) hypertrophy, results from hypertension and aortic …

Altered lipid metabolism characterizes proteinuria and chronic kidney diseases. While it is
thought that dyslipidemia is a consequence of kidney disease, a large body of clinical and …

DISCUSSION Dr. Nosratola D. Vaziri (Chief, Division of Nephrology and Hypertension; and
Professor of Medicine, Physiology, and Biophysics, University of California, Irvine, California …

Clinical strategies focusing on pathogen elimination are expected in an infectious-disease
outbreak, such as the severe coronavirus disease 2019 (COVID-19), to avoid organ …

Background: In nephrotic syndrome, damage to the podocytes of the kidney produces
severe hypercholesterolemia for which novel treatments are urgently needed. PCSK9 …