In the human genome, miR‐451a, miR‐144‐5p (passenger strand), and miR‐144‐3p (guide
strand) reside in clustered microRNA (mi RNA) sequences located within the 17q11. 2 …

Background Huntington's disease (HD) is an inherited disorder caused by the polyglutamine
(poly-Q) mutations of the HTT gene results in neurodegeneration characterized by chorea …

Homeobox genes encode transcription factors which regulate basic processes in
development and cell differentiation and are grouped into classes and subclasses according …

T-box transcription factor 15 (TBX15) is upregulated in a variety of tumors and has been
reported to promote uncontrolled proliferation of tumor cells and induce tumor cells to avoid …

OBJECTIVE: To investigate the role of microRNA-212-5p (miR-212-5p) in clear cell renal
cell carcinoma (ccRCC) and to explore the potential underlying mechanisms. MATERIALS …

Background: Renal cell carcinoma (RCC) is a renal parenchyma neoplasm with a 30%
recurrence rate even when treated properly. MicroRNAs are noncoding small RNAs that are …

TBX15 is a T-box transcription factor essential for development, also proposed as a marker
in prostate cancer; and, recently, its antiapoptotic function indicates a role in carcinogenesis …

TBX15, which encodes a differentiation-related transcription factor, displays promoter-
adjacent DNA hypermethylation in myoblasts and skeletal muscle (psoas) that is absent …

ABSTRACT A major challenge in translating findings from genome-wide association studies
(GWAS) to biological mechanisms is pinpointing functional variants because only a very …

Aim: Possible roles of miRNAs in cancer treatment have been highly studied. This study
aimed to elucidate the role of miR-4732-3p in lung cancer. Methods: Bioinformatics analysis …