Curvature in biological systems: its quantification, emergence, and implications across the scales
B Schamberger, R Ziege, K Anselme… - advanced …, 2023 - Wiley Online Library
Surface curvature both emerges from, and influences the behavior of, living objects at length
scales ranging from cell membranes to single cells to tissues and organs. The relevance of …
scales ranging from cell membranes to single cells to tissues and organs. The relevance of …
Mechanics of 3D cell–hydrogel interactions: experiments, models, and mechanisms
Hydrogels are highly water-swollen molecular networks that are ideal platforms to create
tissue mimetics owing to their vast and tunable properties. As such, hydrogels are promising …
tissue mimetics owing to their vast and tunable properties. As such, hydrogels are promising …
Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers
Actomyosin machinery endows cells with contractility at a single-cell level. However, within a
monolayer, cells can be contractile or extensile based on the direction of pushing or pulling …
monolayer, cells can be contractile or extensile based on the direction of pushing or pulling …
From actin waves to mechanism and back: how theory aids biological understanding
Actin dynamics in cell motility, division, and phagocytosis is regulated by complex factors
with multiple feedback loops, often leading to emergent dynamic patterns in the form of …
with multiple feedback loops, often leading to emergent dynamic patterns in the form of …
Unravelling cell migration: defining movement from the cell surface
F Merino-Casallo, MJ Gomez-Benito… - Cell adhesion & …, 2022 - Taylor & Francis
Cell motility is essential for life and development. Unfortunately, cell migration is also linked
to several pathological processes, such as cancer metastasis. Cells' ability to migrate relies …
to several pathological processes, such as cancer metastasis. Cells' ability to migrate relies …
Cell shape and forces in elastic and structured environments: from single cells to organoids
R Link, K Weißenbruch, M Tanaka… - Advanced Functional …, 2024 - Wiley Online Library
With the advent of mechanobiology, cell shape and forces have emerged as essential
elements of cell behavior and fate, in addition to biochemical factors such as growth factors …
elements of cell behavior and fate, in addition to biochemical factors such as growth factors …
Bridging from single to collective cell migration: A review of models and links to experiments
A Buttenschön, L Edelstein-Keshet - PLoS computational biology, 2020 - journals.plos.org
Mathematical and computational models can assist in gaining an understanding of cell
behavior at many levels of organization. Here, we review models in the literature that focus …
behavior at many levels of organization. Here, we review models in the literature that focus …
Local actin dynamics couple speed and persistence in a cellular Potts model of cell migration
Cell migration is astoundingly diverse. Molecular signatures, cell-cell interactions, and
environmental structures each play their part in shaping cell motion, yielding numerous …
environmental structures each play their part in shaping cell motion, yielding numerous …
Cellular dynamics of myogenic cell migration: molecular mechanisms and implications for skeletal muscle cell therapies
SW Choi, G Ferrari, FS Tedesco - EMBO molecular medicine, 2020 - embopress.org
Directional cell migration is a critical process underlying morphogenesis and post‐natal
tissue regeneration. During embryonic myogenesis, migration of skeletal myogenic …
tissue regeneration. During embryonic myogenesis, migration of skeletal myogenic …
Control of protein-based pattern formation via guiding cues
T Burkart, MC Wigbers, L Würthner, E Frey - Nature Reviews Physics, 2022 - nature.com
Proteins control many vital functions in living cells, such as cell growth and cell division.
Reliable coordination of these functions requires the spatial and temporal organization of …
Reliable coordination of these functions requires the spatial and temporal organization of …