[HTML][HTML] Interleukin-17 family members and inflammation

JK Kolls, A Lindén - Immunity, 2004 - cell.com
IL-17A was cloned more than 10 years ago and six IL-17 family members (IL-17A-F) have
subsequently been described. IL-17A is largely produced by activated memory T …

TH17 cells in development: an updated view of their molecular identity and genetic programming

C Dong - Nature Reviews Immunology, 2008 - nature.com
Following activation, CD4+ T cells differentiate into different lineages of helper T (TH) cells
that are characterized by distinct developmental regulation and biological functions. TH17 …

Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases

M Akdis, S Burgler, R Crameri, T Eiwegger… - Journal of allergy and …, 2011 - Elsevier
Advancing our understanding of mechanisms of immune regulation in allergy, asthma,
autoimmune diseases, tumor development, organ transplantation, and chronic infections …

Interleukin-17 family and IL-17 receptors

TA Moseley, DR Haudenschild, L Rose… - Cytokine & growth factor …, 2003 - Elsevier
Interleukin-17 (IL-17) is a pro-inflammatory cytokine secreted by activated T-cells. Recently
discovered related molecules are forming a family of cytokines, the IL-17 family. The …

The Th17 pathway and inflammatory diseases of the intestines, lungs, and skin

CT Weaver, CO Elson, LA Fouser… - Annual Review of …, 2013 - annualreviews.org
The recent discovery of a new CD4+ T cell subset, Th17, has transformed our understanding
of the pathogenetic basis of an increasing number of chronic immune-mediated diseases …

Identification of IL-17-producing FOXP3+ regulatory T cells in humans

KS Voo, YH Wang, FR Santori… - Proceedings of the …, 2009 - National Acad Sciences
IL-17–producing CD4+ T helper (Th17) cells have recently been defined as a unique subset
of proinflammatory helper cells whose development depends on signaling initiated by IL-6 …

Regulation of inflammatory responses by IL-17F

XO Yang, SH Chang, H Park, R Nurieva… - The Journal of …, 2008 - rupress.org
Although interleukin (IL) 17 has been extensively characterized, the function of IL-17F, which
has an expression pattern regulated similarly to IL-17, is poorly understood. We show that …

[HTML][HTML] IL-17 cytokines and chronic lung diseases

F Ritzmann, LP Lunding, R Bals, M Wegmann… - Cells, 2022 - mdpi.com
IL-17 cytokines are expressed by numerous cells (eg, gamma delta (γδ) T, innate lymphoid
(ILC), Th17, epithelial cells). They contribute to the elimination of bacteria through the …

[HTML][HTML] Much more than IL-17A: cytokines of the IL-17 family between microbiota and cancer

A Brevi, LL Cogrossi, G Grazia… - Frontiers in …, 2020 - frontiersin.org
The interleukin-(IL-) 17 family of cytokines is composed of six members named IL-17A, IL-
17B, IL-17C, IL-17D, IL-17E, and IL-17F. IL-17A is the prototype of this family, and it was the …

The role of Th17 cells in psoriasis

B Li, L Huang, P Lv, X Li, G Liu, Y Chen, Z Wang… - Immunologic …, 2020 - Springer
Abstract T helper 17 (Th17) cells have been involved in the pathogenesis of many
autoimmune and inflammatory diseases, like psoriasis, multiple sclerosis (MS), rheumatoid …