Pneumococcal capsules and their types: past, present, and future
Streptococcus pneumoniae (the pneumococcus) is an important human pathogen. Its
virulence is largely due to its polysaccharide capsule, which shields it from the host immune …
virulence is largely due to its polysaccharide capsule, which shields it from the host immune …
Capsules of Streptococcus pneumoniae and Other Bacteria: Paradigms for Polysaccharide Biosynthesis and Regulation
J Yother - Annual review of microbiology, 2011 - annualreviews.org
Capsular polysaccharides and exopolysaccharides play critical roles in bacterial survival
strategies, and they can have important medical and industrial applications. An immense …
strategies, and they can have important medical and industrial applications. An immense …
Requirement for Capsule in Colonization byStreptococcus pneumoniae
AD Magee, J Yother - Infection and immunity, 2001 - Am Soc Microbiol
Nasopharyngeal colonization is a necessary first step in the pathogenesis of Streptococcus
pneumoniae. Using isolates containing defined mutations in the S. pneumoniae capsule …
pneumoniae. Using isolates containing defined mutations in the S. pneumoniae capsule …
Positive Correlation between Tyrosine Phosphorylation of CpsD and Capsular Polysaccharide Production in Streptococcus pneumoniae
MH Bender, RT Cartee, J Yother - Journal of bacteriology, 2003 - Am Soc Microbiol
ABSTRACT CpsA, CpsB, CpsC, and CpsD are part of a tyrosine phosphorylation regulatory
system involved in modulation of capsule synthesis in Streptococcus pneumoniae and many …
system involved in modulation of capsule synthesis in Streptococcus pneumoniae and many …
[HTML][HTML] Whole genome analysis reveals the diversity and evolutionary relationships between necrotic enteritis-causing strains of Clostridium perfringens
Background Clostridium perfringens causes a range of diseases in animals and humans
including necrotic enteritis in chickens and food poisoning and gas gangrene in humans …
including necrotic enteritis in chickens and food poisoning and gas gangrene in humans …
[HTML][HTML] CpsB is a modulator of capsule-associated tyrosine kinase activity in Streptococcus pneumoniae
MH Bender, J Yother - Journal of Biological Chemistry, 2001 - ASBMB
Tyrosine phosphorylation is associated with polysaccharide synthesis in a number of Gram-
positive and Gram-negative bacteria. In Streptococcus pneumoniae, CpsB, CpsC, and CpsD …
positive and Gram-negative bacteria. In Streptococcus pneumoniae, CpsB, CpsC, and CpsD …
Mutations Blocking Side Chain Assembly, Polymerization, or Transport of a Wzy-Dependent Streptococcus pneumoniae Capsule Are Lethal in the Absence of …
B Xayarath, J Yother - Journal of bacteriology, 2007 - Am Soc Microbiol
Extracellular polysaccharides of many bacteria are synthesized by the Wzy polymerase-
dependent mechanism, where long-chain polymers are assembled from undecaprenyl …
dependent mechanism, where long-chain polymers are assembled from undecaprenyl …
Capsule Biosynthesis and Basic Metabolism inStreptococcus pneumoniae Are Linked through the Cellular Phosphoglucomutase
GG Hardy, MJ Caimano, J Yother - Journal of bacteriology, 2000 - Am Soc Microbiol
Synthesis of the type 3 capsular polysaccharide of Streptococcus pneumoniae requires UDP-
glucose (UDP-Glc) and UDP-glucuronic acid (UDP-GlcUA) for production of the [3)-β-d …
glucose (UDP-Glc) and UDP-glucuronic acid (UDP-GlcUA) for production of the [3)-β-d …
Formation of Streptococcus pneumoniae Non-Phase-Variable Colony Variants Is Due to Increased Mutation Frequency Present under Biofilm Growth Conditions
M Allegrucci, K Sauer - Journal of bacteriology, 2008 - Am Soc Microbiol
In this report, we show that biofilm formation by Streptococcus pneumoniae serotype 19
gives rise to variants (the small mucoid variant [SMV] and the acapsular small-colony variant …
gives rise to variants (the small mucoid variant [SMV] and the acapsular small-colony variant …
Molecular and cellular biology of pneumococcal infection
E Tuomanen - Current opinion in microbiology, 1999 - Elsevier
The complete pneumococcal genome sequence was released in November, 1997. This
advance has been combined with new understanding of physiology and pathogenesis …
advance has been combined with new understanding of physiology and pathogenesis …