Hypoxia is a state of low oxygen tension found in numerous solid tumours. It is typically
associated with abnormal vasculature, which results in a reduced supply of oxygen and …

Piperidine is an important pharmacophore, a privileged scaffold and an excellent
heterocyclic system in the field of drug discovery which provides numerous opportunities in …

Anticancer prodrugs designed to target specifically tumor cells should increase therapeutic
effectiveness and decrease systemic side effects in the treatment of cancer. Over the last 20 …

A simple and efficient protocol to generate amidyl radicals from amine functionalities through
a manganese‐mediated atom‐transfer reaction has been developed. This approach …

The intramolecular haloamination of alkenes is a direct method for the synthesis of
halogenfunctionalized nitrogen heterocycles.[1] Vicinal amino halides are highly versatile …

There are hundreds of ligands which can interact with G-quadruplex DNA, yet very few
which target i-motif. To appreciate an understanding between the dynamics between these …

A metal-free method for intramolecular halocyclization of unfunctionalized olefins was
detailed.(Diacetoxyiodo) benzene (PIDA) was very effective for haloamidation …

Asymmetric catalysis with a chiral (Salen) Mn (III) complex is applied successfully to highly
enantioselective intramolecular haloamination reactions of alkenes through a chiral …

Organocatalytic Stereoselective Iodoamination of Alkenes - Mizar - 2014 - Chemistry – A
European Journal - Wiley Online Library Skip to Article Content Skip to Article Information …

The present review focuses on strategies for the construction of piperidines which have
appeared in the literature since 2003 through mid-2017. In a preceding chapter …