Accurate differential diagnosis of parkinsonism is of paramount therapeutic and prognostic
importance. In addition, with the development of invasive therapies and novel disease …

Navigate PD was an educational program established to supplement existing guidelines
and provide recommendations on the management of Parkinson's disease (PD) refractory to …

The blood–brain barrier (BBB) is a selectively permeable membrane that separates the
bloodstream from the brain. While useful for protecting neural tissue from harmful …

Background Levodopa–carbidopa intestinal gel (LCIG) is available in several countries for
the treatment of advanced levodopa-responsive Parkinson's disease (PD) with severe motor …

Several different strategies are effective for medical treatment of motor problems in
Parkinson's disease (PD). Many guidelines and evidence‐based reviews are available, but …

Background Conventional oral levodopa therapy for the treatment of Parkinson's disease
can be associated with variations in plasma concentrations. Levodopa infusion strategies …

Management of Parkinson's disease (PD) is complicated due to its progressive nature, the
individual patient heterogeneity, and the wide range of signs, symptoms, and daily activities …

An in-depth understanding of the interface between cells and nanostructures is one of the
key challenges for coupling electrically excitable cells and electronic devices. Recently …

The optimization of levodopa is, in most cases, the most powerful therapeutic option
available; however, medication optimization requires an advanced understanding of …

Objective The purpose of this study was to assess the effect of levodopa‐carbidopa
intestinal gel (carbidopa‐levodopa enteral suspension) in advanced Parkinson's disease …