Apoptotic proteins with non-apoptotic activity: expression and function in cancer
V Shoshan-Barmatz, T Arif, A Shteinfer-Kuzmine - Apoptosis, 2023 - Springer
Apoptosis is a process of programmed cell death in which a cell commits suicide while
maintaining the integrity and architecture of the tissue as a whole. Apoptosis involves …
maintaining the integrity and architecture of the tissue as a whole. Apoptosis involves …
CRISPR‐interceded CHO cell line development approaches
S Amiri, S Adibzadeh, S Ghanbari… - Biotechnology and …, 2023 - Wiley Online Library
For industrial production of recombinant protein biopharmaceuticals, Chinese hamster ovary
(CHO) cells represent the most widely adopted host cell system, owing to their capacity to …
(CHO) cells represent the most widely adopted host cell system, owing to their capacity to …
Recent advances in the application of genetic and epigenetic modalities in the improvement of antibody-producing cell lines
SS Baghini, E Razeghian, SK Malayer… - International …, 2023 - Elsevier
There are numerous applications for recombinant antibodies (rAbs) in biological and
toxicological research. Monoclonal antibodies are synthesized using genetic engineering …
toxicological research. Monoclonal antibodies are synthesized using genetic engineering …
Omics and CRISPR in CHO bioproduction: a state-of-the-art review
S Sorourian, A Behzad Behbahani… - Biotechnology and …, 2024 - Springer
Chinese hamster ovary (CHO) cells have been routinely used as a factory for recombinant
proteins for several years, and their improvements have been the focus of consideration …
proteins for several years, and their improvements have been the focus of consideration …
Current strategies for the development of high-yield HEK293 cell lines
L Zhang, J Gao, X Zhang, X Wang, T Wang… - Biochemical Engineering …, 2024 - Elsevier
At present, approximately 80% of the currently approved recombinant therapeutic proteins
are produced by Chinese hamster ovary cells. However, considering that the human …
are produced by Chinese hamster ovary cells. However, considering that the human …
CRISPR‐Cas9 delivery strategies and applications: Review and update
AA Severi, B Akbari - genesis, 2024 - Wiley Online Library
Nowadays, a significant part of the investigations carried out in the medical field belong to
cancer treatment. Generally, conventional cancer treatments, including chemotherapy …
cancer treatment. Generally, conventional cancer treatments, including chemotherapy …
[PDF][PDF] The protective effect of Boesenbergia rotunda extract on cisplatin-exposed human embryonic kidney-293 cells by inhibiting the expression of kidney injury …
Acute kidney injury (AKI) is a major problem in bedridden patients or in platinum-based
chemotherapy patients. This disease is linked with elevated morbidity and mortality …
chemotherapy patients. This disease is linked with elevated morbidity and mortality …
Knockout of BAX and BAK1 Genes and Overexpression of BCL2, BECN1 Genes Increase Lifespan and the Maximum Density of a CHO-S Cell Culture
SV Kovnir, LK Dayanova, EA Gaiamova… - Applied Biochemistry …, 2023 - Springer
Two genome editions have resulted in the CHO cell line 4BGD with homozygous knockouts
of the BAK1, BAX, DHFR and GLUL genes, and overexpression of the BCL2 and BECN1 …
of the BAK1, BAX, DHFR and GLUL genes, and overexpression of the BCL2 and BECN1 …
[HTML][HTML] Time and Cost-Effective Genome Editing Protocol for Simultaneous Caspase 8 Associated Protein 2 Gene Knock in/out in Chinese Hamster Ovary Cells Using …
S Sorourian, AB Behbahani… - Iranian Journal of …, 2024 - ncbi.nlm.nih.gov
Background: CHO cells are preferred for producing biopharmaceuticals, and genome
editing technologies offer opportunities to enhance recombinant protein production …
editing technologies offer opportunities to enhance recombinant protein production …
[PDF][PDF] Identification des substrats de la caspase-8 dans des cellules du cancer colorectal résistantes à l'apoptose
V Létourneau - 2022 - savoirs.usherbrooke.ca
Mémoire présenté à la Faculté de médecine et des sciences de la santé en vue de
l'obtention du diplôme de maitre ès sciences (M. Sc.) en pharmacologie, Faculté de …
l'obtention du diplôme de maitre ès sciences (M. Sc.) en pharmacologie, Faculté de …