Neurodevelopmental disorders such as autism, attention deficit disorder, mental retardation,
and cerebral palsy are common, costly, and can cause lifelong disability. Their causes are …

Expanded research is needed into environmental causation of autism. Children today are
surrounded by thousands of synthetic chemicals. Two hundred of them are neurotoxic in …

N-(1, 3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and its quinone derivative,
6PPD-quinone (6PPD-Q), have been found to be prevalent in the environment, but there are …

In the early 1980s, two water-supply systems on the Marine Corps Base Camp Lejeune in
North Carolina were found to be contaminated with the industrial solvents trichloroethylene …

Abstract Purpose of Review Organophosphate esters (OPEs) are applied to a variety of
consumer products, primarily as flame retardants and plasticizers. OPEs can leach out of …

Idiosyncratic drug induced liver injury (DILI) remains poorly understood. It is assumed that
the affected individuals possess a rare combination of genetic and non genetic factors that, if …

Background The three chemical ultraviolet absorbers benzophenone‐3 (BP‐3), octyl‐
methoxycinnamate (OMC) and 3‐(4‐methylbenzylidene) camphor (4‐MBC) are …

Following a request from the European Commission to EFSA, the EFSA Scientific Committee
(SC) prepared a guidance for the risk assessment of substances present in food intended for …

In clinical development stages, an a priori assessment of the sensitivity of the
pharmacokinetic behavior with respect to physiological and anthropometric properties of …

Background and objective Clearance is an important pharmacokinetic concept for scaling
dosage, understanding the risks of drug-drug interactions and environmental risk …