Comprehensive insights into medicinal research on imidazole-based supramolecular complexes

SR Li, YM Tan, L Zhang, CH Zhou - Pharmaceutics, 2023 - mdpi.com
The electron-rich five-membered aromatic aza-heterocyclic imidazole, which contains two
nitrogen atoms, is an important functional fragment widely present in a large number of …

Development of new 2-(Benzothiazol-2-ylimino)-2, 3-dihydro-1H-imidazol-4-ol complexes as a robust catalysts for synthesis of thiazole 6-carbonitrile derivatives …

MAEAA Ali, O Elhady, A Abdou… - Journal of Molecular …, 2023 - Elsevier
Abstract Here, using Pd 2+, Fe 3+, and Ni 2+ ions, we established new imidazole
complexes. These complexes were described in the initial section to provide their chemical …

Design, synthesis, spectroscopic inspection, DFT and molecular docking study of metal chelates incorporating azo dye ligand for biological evaluation

MAI Al-Gaber, HM Abd El-Lateef, MM Khalaf… - Materials, 2023 - mdpi.com
A new heterocyclic azo dye ligand (L) was synthesized by the combination of 4-amino
antipyrine with 4-aminophenol. The new Cr (III), Mn (II), Fe (III), Co (II), Ni (II), Cu (II), Zn (II) …

Synthesis and characterization of Fe (III), Pd (II) and Cu (II)-thiazole complexes; DFT, pharmacophore modeling, in-vitro assay and DNA binding studies

AM Abu-Dief, NM El-Metwaly, SO Alzahrani… - Journal of Molecular …, 2021 - Elsevier
New pharmacologically active complexes were prepared from Pd (II), Fe (III), and Cu (II) ions
with 2-amino-6-oxo-3-(piperidinylamidino)-4-(4methoxyphenyl)-6, 7-dihydro-pyrano [2, 3-d] …

Coordination compounds of biogenic metals as cytotoxic agents in cancer therapy

DA Guk, OO Krasnovskaya… - Russian Chemical …, 2021 - iopscience.iop.org
The review summarizes the data on the structures and methods for the synthesis of
compounds with anticancer activity based on biogenic metals, which can replace platinum …

Tailoring of some novel bis-hydrazone metal chelates, spectral based characterization and DFT calculations for pharmaceutical applications and in-silico treatments …

HA Qasem, MR Aouad, HA Al-Abdulkarim… - Journal of Molecular …, 2022 - Elsevier
A series of new bis-hydrazone complexes was obtained from ((N'E, N'''E)-2, 2′-(1, 3-
phenylenebis (oxy)) bis (N'-(4, 5-di-tert-butyl-2-hydroxybenzylidene) acetohydrazide)) ligand …

Synthesis and characterization of new Cr (III), Fe (III) and Cu (II) complexes incorporating multi-substituted aryl imidazole ligand: Structural, DFT, DNA binding, and …

AM Abu-Dief, LH Abdel-Rahman… - … Acta Part A: Molecular …, 2020 - Elsevier
Designing new metal-based molecular antibiotics is an efficient approach to overcome the
growing threat of antimicrobial resistance. In this paper, novel Cr (III), Fe (III) and Cu (II) …

Design, synthesis, structural inspection of Pd2+, VO2+, Mn2+, and Zn2+ chelates incorporating ferrocenyl thiophenol ligand: DNA interaction and pharmaceutical …

ET Aljohani, MR Shehata… - Applied Organometallic …, 2021 - Wiley Online Library
Some new transition metal chelates ([M (FSH) 2] and [M (FSH)(CH3COO− or NO3−)], where
M= Pd2+, VO2+, Mn2+, Zn2+, and cations) incorporating ferrocenyl thiophenol imine ligand …

[HTML][HTML] Fabrication, DFT calculation, and molecular docking of two Fe (III) imine chelates as anti-COVID-19 and pharmaceutical drug candidate

HMA El-Lateef, MM Khalaf, MR Shehata… - International journal of …, 2022 - mdpi.com
Two tetradentate dibasic chelating Schiff base iron (III) chelates were prepared from the
reaction of 2, 2′-((1E, 1′ E)-(1, 2-phenylenebis (azanylylidene)) bis (methanylylidene)) bis …

Development of new azomethine metal chelates derived from isatin: DFT and Pharmaceutical Studies

AA Al-Shamry, MM Khalaf, HMA El-Lateef, TA Yousef… - Materials, 2022 - mdpi.com
Through the condensation of isatin (indoline-2, 3-dione) and aniline in a 1: 1 ratio, a Schiff
base ligand was synthesized and characterized via (1H-NMR, mass, IR, UV-Vis) spectra …