Tutorial: multivariate classification for vibrational spectroscopy in biological samples

CLM Morais, KMG Lima, M Singh, FL Martin - Nature Protocols, 2020 - nature.com
Vibrational spectroscopy techniques, such as Fourier-transform infrared (FTIR) and Raman
spectroscopy, have been successful methods for studying the interaction of light with …

A comprehensive review of Design of experiment (DOE) for water and wastewater treatment application-Key concepts, methodology and contextualized application

BCY Lee, MS Mahtab, TH Neo, IH Farooqi… - Journal of Water …, 2022 - Elsevier
Abstract Design of experiment (DOE) is a robust design methodology that can be used to
solve various water engineering problems. It aims to obtain the maximal results from data …

Statistical design of experiments for synthetic biology

J Gilman, L Walls, L Bandiera… - ACS synthetic …, 2021 - ACS Publications
The design and optimization of biological systems is an inherently complex undertaking that
requires careful balancing of myriad synergistic and antagonistic variables. However …

Implementation of liquid chromatography–high resolution mass spectrometry methods for untargeted metabolomic analyses of biological samples: A tutorial

J Pezzatti, J Boccard, S Codesido, Y Gagnebin… - Analytica chimica …, 2020 - Elsevier
Untargeted metabolomics is now widely recognized as a useful tool for exploring metabolic
changes taking place in biological systems under different conditions. By its nature, this is a …

From samples to insights into metabolism: Uncovering biologically relevant information in LC-HRMS metabolomics data

J Ivanisevic, EJ Want - Metabolites, 2019 - mdpi.com
Untargeted metabolomics (including lipidomics) is a holistic approach to biomarker
discovery and mechanistic insights into disease onset and progression, and response to …

Approaches in metabolomics for regulatory toxicology applications

E Olesti, V González-Ruiz, MF Wilks, J Boccard… - Analyst, 2021 - pubs.rsc.org
Innovative methodological approaches are needed to conduct human health and
environmental risk assessments on a growing number of marketed chemicals. Metabolomics …

[HTML][HTML] Critical analysis of green extraction techniques used for botanicals: Trends, priorities, and optimization strategies-A review

C Cannavacciuolo, S Pagliari, R Celano… - TrAC Trends in …, 2024 - Elsevier
Botanicals are widely used and marketed as food supplements or cosmetics with particular
benefits for human health. Botanicals are products manufactured using natural components …

Metabolomics, a powerful tool for understanding plant abiotic stress

FP Carrera, C Noceda, MG Maridueña-Zavala… - Agronomy, 2021 - mdpi.com
Metabolomics is a technology that generates large amounts of data and contributes to
obtaining wide and integral explanations of the biochemical state of a living organism …

[HTML][HTML] New insights into the biodegradation of chlorpyrifos by a novel bacterial consortium: process optimization using general factorial experimental design

S Uniyal, RK Sharma, V Kondakal - Ecotoxicology and Environmental …, 2021 - Elsevier
Himalayan mountains are subjected to the intensive and unjudicial application of
chlorpyrifos (CP) in agricultural practices; hence it has spurred concerns over food safety …

Application of mixture design in analytical chemistry

MA Bezerra, VA Lemos, CG Novaes, RM de Jesus… - Microchemical …, 2020 - Elsevier
This manuscript approaches the use of mixture design in the optimization of any stage of an
analytical method. In addition to addressing the basic principles of this type of design …