Epidemiology and prevention of prostate cancer

G Gandaglia, R Leni, F Bray, N Fleshner… - European urology …, 2021 - Elsevier
Abstract Context Worldwide, prostate cancer (PCa) represents the second most common
solid tumor in men. Objective To assess the geographical distribution of PCa …

EAU-EANM-ESTRO-ESUR-SIOG guidelines on prostate cancer—2020 update. Part 1: screening, diagnosis, and local treatment with curative intent

N Mottet, RCN van den Bergh, E Briers… - European urology, 2021 - Elsevier
Objective To present a summary of the 2020 version of the European Association of Urology
(EAU)-European Association of Nuclear Medicine (EANM)-European Society for …

Early detection of prostate cancer: AUA/SUO guideline part I: prostate cancer screening

JT Wei, D Barocas, S Carlsson, F Coakley… - Journal of …, 2023 - journals.lww.com
Purpose: The summary presented herein covers recommendations on the early detection of
prostate cancer and provides a framework to facilitate clinical decision-making in the …

BRCA mutations in ovarian and prostate cancer: bench to bedside

S Boussios, E Rassy, M Moschetta, A Ghose… - Cancers, 2022 - mdpi.com
Simple Summary DNA damage is one of the hallmarks of cancer. Epithelial ovarian cancer
(EOC)—especially the high-grade serous subtype—harbors a defect in at least one DNA …

Risk reduction and screening of cancer in hereditary breast-ovarian cancer syndromes: ESMO Clinical Practice Guideline☆

C Sessa, J Balmaña, SL Bober… - Annals of …, 2023 - annalsofoncology.org
Hereditary breast and ovarian cancer syndrome (HBOC) is clinically defined by family
history criteria, and molecularly defined by identification of germline pathogenic variants …

Implementation of germline testing for prostate cancer: Philadelphia Prostate Cancer Consensus Conference 2019

VN Giri, KE Knudsen, WK Kelly, HH Cheng… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Germline testing (GT) is a central feature of prostate cancer (PCA) treatment,
management, and hereditary cancer assessment. Critical needs include optimized …

Hereditary prostate cancer: genes related, target therapy and prevention

MT Vietri, G D'elia, G Caliendo, M Resse… - International journal of …, 2021 - mdpi.com
Prostate cancer (PCa) is globally the second most diagnosed cancer type and the most
common cause of cancer-related deaths in men. Family history of PCa, hereditary breast …

Prostate cancer and PARP inhibitors: progress and challenges

D Teyssonneau, H Margot, M Cabart… - Journal of Hematology & …, 2021 - Springer
Despite survival improvements achieved over the last two decades, prostate cancer remains
lethal at the metastatic castration-resistant stage (mCRPC) and new therapeutic approaches …

BRCA mutations in prostate cancer: assessment, implications and treatment considerations

S Shah, R Rachmat, S Enyioma, A Ghose… - International Journal of …, 2021 - mdpi.com
Prostate cancer ranks fifth in cancer-related mortality in men worldwide. DNA damage is
implicated in cancer and DNA damage response (DDR) pathways are in place against this …

Genetic risk prediction for prostate cancer: implications for early detection and prevention

TM Seibert, IP Garraway, A Plym, BA Mahal, V Giri… - European urology, 2023 - Elsevier
Abstract Context Prostate cancer (PCa) is a leading cause of death and partially heritable.
Genetic risk prediction might be useful for strategies to reduce PCa mortality through early …