Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis
Nanotechnology could improve our understanding of the pathophysiology of atherosclerosis
and contribute to the development of novel diagnostic and therapeutic strategies to further …
and contribute to the development of novel diagnostic and therapeutic strategies to further …
New opportunities and old challenges in the clinical translation of nanotheranostics
Nanoparticle-based systems imbued with both diagnostic and therapeutic functions, known
as nanotheranostics, have enabled remarkable progress in guiding focal therapy, inducing …
as nanotheranostics, have enabled remarkable progress in guiding focal therapy, inducing …
Atherosclerotic plaque healing
R Vergallo, F Crea - New England journal of medicine, 2020 - Mass Medical Soc
Atherosclerotic Plaque Healing Atherosclerotic plaque rupture and erosion result in acute
coronary syndromes. Plaque healing after initial disruption has been less extensively …
coronary syndromes. Plaque healing after initial disruption has been less extensively …
Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association
JF Meschia, C Bushnell, B Boden-Albala, LT Braun… - Stroke, 2014 - Am Heart Assoc
The aim of this updated statement is to provide comprehensive and timely evidence-based
recommendations on the prevention of stroke among individuals who have not previously …
recommendations on the prevention of stroke among individuals who have not previously …
Application of light scattering techniques to nanoparticle characterization and development
Over the years, the scientific importance of nanoparticles for biomedical applications has
increased. The high stability and biocompatibility, together with the low toxicity of the …
increased. The high stability and biocompatibility, together with the low toxicity of the …
Foam cell formation: A new target for fighting atherosclerosis and cardiovascular disease
EM Maguire, SWA Pearce, Q Xiao - Vascular Pharmacology, 2019 - Elsevier
During atherosclerosis, the gradual accumulation of lipids into the subendothelial space of
damaged arteries results in several lipid modification processes followed by macrophage …
damaged arteries results in several lipid modification processes followed by macrophage …
Mechanisms of acute coronary syndromes and their implications for therapy
P Libby - New England Journal of Medicine, 2013 - Mass Medical Soc
The notion that heart attacks develop from coronary-artery stenosis is an oversimplification
of a process involving lipid metabolism, inflammation, macrophage activation, collagen …
of a process involving lipid metabolism, inflammation, macrophage activation, collagen …
Imaging macrophages with nanoparticles
Nanomaterials have much to offer, not only in deciphering innate immune cell biology and
tracking cells, but also in advancing personalized clinical care by providing diagnostic and …
tracking cells, but also in advancing personalized clinical care by providing diagnostic and …
Towards clinically translatable in vivo nanodiagnostics
Nanodiagnostics as a field makes use of fundamental advances in nanobiotechnology to
diagnose, characterize and manage disease at the molecular scale. As these strategies …
diagnose, characterize and manage disease at the molecular scale. As these strategies …
2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart …
P Greenland, JS Alpert, GA Beller, EJ Benjamin… - Journal of the American …, 2010 - jacc.org
The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted for the period beginning March 2008 through …
extensive evidence review was conducted for the period beginning March 2008 through …