Glutamate is a ubiquitous excitatory neurotransmitter, which is involved in normal
physiology, a variety of central nervous system (CNS) functions, including excitotoxicity and …

Individuals with obsessive–compulsive disorder (OCD) have also been shown to have
comorbid lifetime diagnoses of major depressive disorder (MDD; rates greater than 70%) …

Considerable variation is evident in response to psychological therapies for mood and
anxiety disorders. Genetic factors alongside environmental variables and gene-environment …

Rationale In clinical practice, ketamine, an antagonist of the N-methyl-d-aspartate receptor
(NMDAR), is used to alleviate depressive symptoms in patients with major depressive …

Autism spectrum disorders (ASDs) and obsessive compulsive disorder (OCD) are often
comorbid with the overlap based on compulsive behaviors. Although previous studies …

Autism spectrum disorder (ASD) and obsessive–compulsive disorder (OCD) are both
common pediatric psychiatric conditions with a prevalence of rate in recent studies of 1% to …

Abstract Obsessive-Compulsive Disorder (OCD) is a prevalent and severe clinical condition
whose hallmarks are excessive, unwanted thoughts (obsessions) and repetitive behaviors …

Objective Obsessive-compulsive disorder (OCD) is common and debilitating with patients
exhibiting persistent intrusive thoughts (obsessions), repetitive ritualistic behaviours …

Up to 30% of patients with obsessive-compulsive disorder (OCD) exhibit an inadequate
response to serotonin reuptake inhibitors (SRIs). To date, genetic predictors of OCD …

Abstract Obsessive Compulsive Disorder (OCD) is a common neuropsychiatric disorder with
unknown molecular underpinnings. Identification of genetic and non-genetic risk factors has …