Exploring pharmacological significance of chalcone scaffold: a review

NK Sahu, SS Balbhadra… - Current medicinal …, 2012 - ingentaconnect.com
Chalcones (1, 3-diaryl-2-propen-1-ones) and their heterocyclic analogues, belong to the
flavonoid family, which possess a number of interesting biological properties such as …

Synthesis and pharmacological properties of chalcones: a review

SL Gaonkar, UN Vignesh - Research on chemical intermediates, 2017 - Springer
Chalcones and their analogs have been an area of great interest in recent years. Numerous
research papers have been published, and chalcones continue to show promise for new …

Trends in utilization of the pharmacological potential of chalcones

DI Batovska, IT Todorova - Current clinical pharmacology, 2010 - ingentaconnect.com
Chalcones (1, 3-diaryl-2-propen-1-ones) are open chain flavonoids that are widely
biosynthesized in plants. They are important for the pigmentation of flowers and, hence, act …

Synthesis, antioxidant evaluation, and quantitative structure–activity relationship studies of chalcones

PM Sivakumar, PK Prabhakar, M Doble - Medicinal Chemistry Research, 2011 - Springer
Synthesis, antioxidant activity, and quantitative structure–activity relationship (QSAR) of 25
of chalcone derivatives is reported here. They were synthesized by Claisen–Schmidt …

Synthesis and antimicrobial activity of some chalcone derivatives

YR Prasad, AL Rao, R Rambabu - Journal of Chemistry, 2008 - Wiley Online Library
In an effort to develop antimicrobial agents, a series of chalcones were prepared by Claisen‐
Schmidt condensation of appropriate acetophenones with appropriate aromatic aldehydes …

Recent developments in biological aspects of chalcones: the odyssey continues

A Rani, A Anand, K Kumar, V Kumar - Expert opinion on drug …, 2019 - Taylor & Francis
Introduction: Chalcones are attractive to synthetic chemists because they are easy to
prepare, have a large number of replaceable hydrogens, thereby having significant …

Synthesis and biological evaluation of chalcone derivatives (mini review)

S Nasir Abbas Bukhari, M Jasamai… - Mini reviews in …, 2012 - ingentaconnect.com
Chalcones are the principal precursors for the biosynthesis of flavonoids and isoflavonoids.
A three carbon α, β-unsaturated carbonyl system constitutes chalcones. Chalcones are the …

[PDF][PDF] Chemical and structural properties of chalcones I

BE Aksöz, R Ertan - Fabad J Pharm Sci, 2011 - dergi.fabad.org.tr
Chalcones belong to the flavonoid family and display several pharmacological activities
which are very important. They can be used as an initial compound for synthesis of a lot of …

Antimycobacterial activity of two natural alkaloids, vasicine acetate and 2-acetyl benzylamine, isolated from Indian shrub Adhatoda vasica Ness. leaves

S Ignacimuthu, N Shanmugam - Journal of biosciences, 2010 - Springer
In folk medicine, Adhatoda vasica Ness.(Acanthaceae) is used to treat asthma and cough.
The leaves of A. vasica were powdered and extracted with hexane, ethyl acetate and …

Synthesis, biological evaluation, and molecular modeling of chalcone derivatives as potent inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatases …

LD Chiaradia, PGA Martins, MNS Cordeiro… - Journal of medicinal …, 2012 - ACS Publications
Tuberculosis (TB) is a major infectious disease caused by Mycobacterium tuberculosis
(Mtb). According to the World Health Organization (WHO), about 1.8 million people die from …