Abstract Significance: Hydrogen sulfide (H2S) has been recognized as the third gaseous
transmitter alongside nitric oxide and carbon monoxide. In the past decade, numerous …

Trauma experienced during surgery can contribute to the development of a systemic
inflammatory response that can cause multi-organ dysfunction or even failure. Post-surgical …

Thiosulfate in the form of sodium thiosulfate (STS) is a major oxidation product of hydrogen
sulfide (H2S), an endogenous signaling molecule and the third member of the …

Introduction Alpha-lipoic acid (ALA) is a licensed drug for the treatment of diabetic
neuropathy. We recently reported that it also improves diabetic cardiomyopathy (DCM) in …

Introduction We previously reported that alpha-lipoic acid (ALA) supplementation protects
against progression of diabetic kidney disease (DKD). In this study, we aim to investigate …

Cold ischemia-reperfusion injury (IRI) is an inevitable and unresolved problem that poses a
great challenge in solid organ transplantation (SOT). It represents a major factor that …

Acute kidney injury (AKI) is a syndrome affecting most patients hospitalized due to kidney
disease; it accounts for 15% of patients hospitalized in intensive care units worldwide. AKI is …

This study investigates the molecular mechanisms of the nephroprotective effect of
piceatannol (PIC) against cisplatin-induced nephrotoxicity in rats. PIC (10 mg/kg ip) was …

Hydrogen sulfide (H 2 S) is synthesized in nearly all organ systems including the kidney.
Recent findings have revealed that H 2 S functions as a gasotransmitter affecting a wide …

Aims: Cisplatin (CDDP) is an effective antineoplastic agent, however, its serious
nephrotoxicity limits therapeutic use. Human growth hormone (hGH) has proved antioxidant …