Retinitis pigmentosa (RP) encompasses a group of inherited retinal dystrophies
characterized by the primary degeneration of rod and cone photoreceptors. RP is a leading …

Hereditary degenerations of the human retina are genetically heterogeneous, with well over
100 genes implicated so far. This Seminar focuses on the subset of diseases called retinitis …

Optical coherence tomographic angiography (OCTA) is a novel technology capable of
imaging retinal vasculature three-dimensionally at capillary scale without the need to inject …

The pattern electroretinogram (PERG) provides an objective measure of central retinal
function, and has become an important element of the author's clinical visual …

Importance Determining the annual rate of change in the width of the inner segment
ellipsoid zone (EZ; ie, inner/outer segment border) in the context of short-term variability …

BACKGROUND: Retinitis pigmentosa (RP) is a heterogeneous group of inherited retinal
disorders characterized by progressive photoreceptor apoptosis. It is the leading cause of …

OBJECTIVE: To provide the first measures of the relative rates of rod and cone functional
loss in patients with retinitis pigmentosa (RP) or cone-rod dystrophy (CRD). DESIGN: Five …

purpose. To measure the rate of progression of retinal degeneration in patients with retinitis
pigmentosa due to dominant rhodopsin mutations and to determine whether the rate of …

Pre-clinical trials of treatment in retinal degenerations have shown progress toward
preventing loss or restoring function of rod photoreceptors. In anticipation of human clinical …

purpose. To measure the rates of visual acuity, visual field, and ERG loss in patients with X-
linked retinitis pigmentosa due to RPGR mutations and to determine whether these rates …