In this report, we demonstrate an interaction between subtilisin NAT (formerly designated
BSP, or nattokinase), a profibrinolytic serine proteinase from Bacillus subtilis, and …

Tissue plasminogen activator (tPA), a neuronal as well as the key fibrinolytic enzyme, is
found concentrated on demyelinated axons in multiple sclerosis lesions together with fibrin …

Thrombolytic therapy is effective in paroxysmal nocturnal hemoglobinuria: a series of nine
patients and a review of the literature - PMC Back to Top Skip to main content NIH NLM Logo …

Total fibrinolytic activity in the vasculature is finely tuned by the balance between tissue
plasminogen activator and plasminogen activator inhibitor type 1 (PAI-1). Although PAI-1 …

We analyzed the secretory dynamics of tissue plasminogen activator (tPA) in EA. hy926
cells, an established vascular endothelial cell (VEC) line producing GFP-tagged tPA, using …

BACKGROUND: Recombinant activated factor VII (rFVIIa) is increasingly used for treating
refractory bleeding after cardiac surgery. However, hemostasis also depends on coagulation …

Iron salts are used in the treatment of iron deficiency anemia. Diabetic patients are
frequently anemic and treatment includes administration of iron. Anemic patients on …

Background: The development of global tests for the fibrinolytic capacity in blood is
hampered by the low base‐line fibrinolytic activity in blood, by the involvement of both …

Objective To study the mechanism associated with the development of symptomatic
disseminated intravascular coagulation (DIC) after head injury. Methods Plasma parameters …

Several activated coagulation factors have been reported to enhance fibrinolysis by
neutralizing plasminogen activator inhibitor type 1 (PAI-1) activity. We evaluated the …