Extensive research has found strongly increased generation of reactive oxygen species, free
radicals, and reactive nitrogen species during acute physical exercise that can lead to …

Sarcopenia, an age-associated decline in skeletal muscle mass coupled with functional
deterioration, may be exacerbated by obesity leading to higher disability, frailty, morbidity …

Obesity-associated inflammation is a systemic process that affects all metabolic organs.
Prominent among these is adipose tissue, where cells of the innate and adaptive immune …

The epidemic of diabetes mellitus has already become a serious global health threat. In the
past three decades, the number of people with diabetes mellitus has quadrupled globally …

Melatonin possesses the indoleamine structure and exerts antioxidant and anti-inflammatory
actions and other physiological properties. Physical exercise can influence secretion of …

This systematic review examined the effect of exercise training interventions on physical
fitness in adults with overweight or obesity and compared the effectiveness of different types …

Previous reports have shown that exercise improves serum leptin and adiponectin
abnormalities in overweight and obese individuals; however, results to date are …

Age-associated hyper-inflammation or “inflamm-aging” has been linked to the development
of chronic diseases and characterized as an unavoidable aspect of aging. However, the …

Adiponectin regulates metabolism through blood glucose control and fatty acid oxidation,
partly mediated by downstream effects of adiponectin signaling in skeletal muscle. More …

The improvement in survival of childhood cancer observed across the past 50 years has
resulted in a growing acknowledgment that simply extending the lifespan of survivors is not …