Cell-based assays: fuelling drug discovery

E Michelini, L Cevenini, L Mezzanotte, A Coppa… - Analytical and …, 2010 - Springer
It has been estimated that over a billion dollars in resources can be consumed to obtain
clinical approval, and only a few new chemical entities are approved by the US Food and …

Combining surface topography with polymer chemistry: exploring new interfacial biological phenomena

D Li, Q Zheng, Y Wang, H Chen - Polymer chemistry, 2014 - pubs.rsc.org
The review focuses on the combination of surface topography and surface chemical
modification with the grafting of polymer chains to develop optimal material interfaces for …

Role of trapped air in the formation of cell-and-protein micropatterns on superhydrophobic/superhydrophilic microtemplated surfaces

Q Huang, L Lin, Y Yang, R Hu, EA Vogler, C Lin - Biomaterials, 2012 - Elsevier
Air trapped within the interstices of TiO2 nanotube surfaces bearing superhydrophobic/
superhydrophilic microtemplated domains controls formation of protein micropatterns but not …

Surface modification to control protein/surface interactions

L Yuan, Q Yu, D Li, H Chen - Macromolecular bioscience, 2011 - Wiley Online Library
Protein/surface interactions are well known to play an important role in various biological
phenomena and to determine the ultimate biofunctionality of a given material once it is in …

Commercialization of microcavity plasma devices and arrays: Systems for VUV photolithography and nanopatterning, disinfection of drinking water and air, and biofilm …

J Kim, AE Mironov, JH Cho, DS Sievers… - Plasma Processes …, 2022 - Wiley Online Library
A little more than two decades after the introduction of the first microcavity plasma devices, a
growing body of commercial products based on the remarkable properties of these low …

[HTML][HTML] Photolithography in the vacuum ultraviolet (172 nm) with sub-400 nm resolution: photoablative patterning of nanostructures and optical components in bulk …

AE Mironov, J Kim, Y Huang, AW Steinforth, DJ Sievers… - Nanoscale, 2020 - pubs.rsc.org
Precision photoablation of bulk polymers or films with incoherent vacuum ultraviolet (VUV)
radiation from flat, microplasma array-powered lamps has led to the realization of a …

Ion beam etching titanium for enhanced osteoblast response

NA Riedel, JD Williams, KC Popat - Journal of materials science, 2011 - Springer
As the demand for hip and knee replacements continues to grow, researchers look to
increase the operational lifetimes of these implants. Many implant failures are attributed to …

Effects of the morphology of sulfobetaine zwitterionic layers grafted onto a silicone surface on improving the hydrophilic stability, anti‐bacterial adhesion properties …

Q Cao, S Wu, L Wang, X Shi, G Li - Journal of Applied Polymer …, 2018 - Wiley Online Library
Though silicone rubber has been used in the biomedical field, its inherent hydrophobic
nature and “hydrophobic recovery” limit its wide application. In this article, cross‐linked and …

[HTML][HTML] Functionalized stress component onto bio-template as a pathway of cytocompatibility

M Keshavarz, B Tan, K Venkatakrishnan - Scientific reports, 2016 - nature.com
This in-vitro study introduces residual stress as a third dimension of cell stimulus to modulate
the interaction between cells and bio-template, without the addition of either chemical or …

Patterning surfaces for controlled platelet adhesion and detection of dysfunctional platelets

W Ye, Q Shi, SC Wong, J Hou, H Shi… - Macromolecular …, 2013 - Wiley Online Library
Platelets play a fundamental role in thrombus formation and in the pathogenesis of arterial
thrombosis. Patterning surfaces for controlled platelet adhesion paves the way for adhesion …