The prescription opioid epidemic: an overview for anesthesiologists

A Alam, DN Juurlink - Canadian Journal of Anesthesia, 2016 - search.proquest.com
Purpose The objectives for preparing this article were to review the historical context and
epidemiology surrounding the North American prescription opioid crisis, to summarize the …

Optimizing the management of chronic pain in sickle cell disease

I Osunkwo, HF O'Connor, E Saah - Hematology 2014, the …, 2020 - ashpublications.org
Chronic pain in sickle cell disease (SCD) refers to pain present on most days lasting over six
months. It can start during childhood and the prevalence increases with age. By adulthood …

European clinical practice recommendations on opioids for chronic noncancer pain–Part 2: Special situations

N Krčevski Škvarč, B Morlion, KE Vowles… - … Journal of Pain, 2021 - Wiley Online Library
Background Opioid use for chronic non‐cancer pain (CNCP) is under debate. In the
absence of pan‐European guidance on this issue, a position paper was commissioned by …

Pancreatic QST differentiates chronic pancreatitis patients into distinct pain phenotypes independent of psychiatric comorbidities

M Faghih, AE Phillips, L Kuhlmann, E Afghani… - Clinical …, 2022 - Elsevier
Background & Aims Quantitative sensory testing (QST) has been previously used to study
pain in chronic pancreatitis (CP) but included methods that are not suitable for clinical …

Opioids and chronic pain: where is the balance?

MP Davis, Z Mehta - Current oncology reports, 2016 - Springer
Chronic opioid therapy (defined as greater than 3 months on opioids) is a common practice
for those with non-cancer pain, cancer survivors with treatment-related pain, and individuals …

Divergent profiles of fentanyl withdrawal and associated pain in mice and rats

O Uddin, C Jenne, ME Fox, K Arakawa, A Keller… - Pharmacology …, 2021 - Elsevier
Opioid abuse has devastating effects on patients, their families, and society. Withdrawal
symptoms are severely unpleasant, prolonged, and frequently hinder recovery or lead to …

Assessing pain in persons with opioid use disorder: Approaches, techniques and special considerations

JC Nunes, GPA Costa, J Weleff… - British Journal of …, 2024 - Wiley Online Library
Pain and opioid use disorder (OUD) are inextricably linked, as the former can be a risk factor
for the development of the latter, and over a third of persons with OUD suffer concomitant …

Opioid medication use in patients with gastrointestinal diagnoses vs unexplained gastrointestinal symptoms in the US Veterans Health Administration

GS Sayuk, N Kanuri, CP Gyawali… - Alimentary …, 2018 - Wiley Online Library
Background While opioid prescriptions have increased alarmingly in the United States (US),
their use for unexplained chronic gastrointestinal (GI) pain (eg, irritable bowel syndrome) …

Systemic morphine produces dose-dependent nociceptor-mediated biphasic changes in nociceptive threshold and neuroplasticity

LF Ferrari, D Araldi, O Bogen, PG Green, JD Levine - Neuroscience, 2019 - Elsevier
We investigated the dose dependence of the role of nociceptors in opioid-induced side-
effects, hyperalgesia and pain chronification, in the rat. Systemic morphine produced a dose …

Withdrawal-associated injury site pain (WISP): a descriptive case series of an opioid cessation phenomenon

LM Rieb, WV Norman, RE Martin, J Berkowitz, E Wood… - Pain, 2016 - journals.lww.com
Withdrawal-associated injury site pain (WISP): a descriptive... : PAIN Withdrawal-associated
injury site pain (WISP): a descriptive case series of an opioid cessation phenomenon : PAIN …