Bacteriocins: An Overview of Antimicrobial, Toxicity, and Biosafety Assessment by in vivo Models

DF Benítez-Chao, A León-Buitimea… - Frontiers in …, 2021 - frontiersin.org
The world is facing a significant increase in infections caused by drug-resistant infectious
agents. In response, various strategies have been recently explored to treat them, including …

A review: the fate of bacteriocins in the human gastro-intestinal tract: do they cross the gut–blood barrier?

LMT Dicks, L Dreyer, C Smith… - Frontiers in …, 2018 - frontiersin.org
The intestinal barrier, consisting of the vascular endothelium, epithelial cell lining, and
mucus layer, covers a surface of about 400 m2. The integrity of the gut wall is sustained by …

The antimicrobial peptide SAAP-148 combats drug-resistant bacteria and biofilms

A de Breij, M Riool, RA Cordfunke… - Science translational …, 2018 - science.org
Development of novel antimicrobial agents is a top priority in the fight against multidrug-
resistant (MDR) and persistent bacteria. We developed a panel of synthetic antimicrobial …

Molecular insights into probiotic mechanisms of action employed against intestinal pathogenic bacteria

WF Van Zyl, SM Deane, LMT Dicks - Gut microbes, 2020 - Taylor & Francis
Gastrointestinal (GI) diseases, and in particular those caused by bacterial infections, are a
major cause of morbidity and mortality worldwide. Treatment is becoming increasingly …

Eradication of Multidrug‐Resistant Staphylococcal Infections by Light‐Activatable Micellar Nanocarriers in a Murine Model

Y Liu, HC van der Mei, B Zhao, Y Zhai… - Advanced Functional …, 2017 - Wiley Online Library
Bacterial infections are mostly due to bacteria in their biofilm mode‐of‐growth, making them
recalcitrant to antibiotic penetration. In addition, the number of bacterial strains intrinsically …

Therapeutic application of lantibiotics and other lanthipeptides: old and new findings

ADP van Staden, WF van Zyl, M Trindade… - Applied and …, 2021 - Am Soc Microbiol
Lanthipeptides are ribosomally synthesized and posttranslationally modified peptides, with
modifications that are incorporated during biosynthesis by dedicated enzymes. Various …

Probiotics and their effect on surgical wound healing: a systematic review and new insights into the role of nanotechnology

A Bekiaridou, E Karlafti, IM Oikonomou, A Ioannidis… - Nutrients, 2021 - mdpi.com
Skin tissue repair is of fundamental importance for maintaining homeostasis regulation,
protection barrier, absorption, and excretion of skin tissue. Wound healing is a complicated …

Emerging frontiers in microbiome engineering

ME Inda, E Broset, TK Lu, C de la Fuente-Nunez - Trends in immunology, 2019 - cell.com
The gut microbiome has a significant impact on health and disease and can actively
contribute to obesity, diabetes, inflammatory bowel disease, cardiovascular disease, and …

Combined photothermal and antibiotic therapy for bacterial infection via acidity-sensitive nanocarriers with enhanced antimicrobial performance

D He, T Yang, W Qian, C Qi, L Mao, X Yu, H Zhu… - Applied Materials …, 2018 - Elsevier
Integration of two distinctive bactericides into one platform is a promising strategy to
enhance the efficiency of antimicrobial agents. We reported an efficient chemo-photothermal …

Anti-inflammatory and wound healing properties of lactic acid bacteria and its peptides

P Saravanan, N Balachander, KRS K - Folia Microbiologica, 2023 - Springer
Recent studies manifest an increase of inflammatory diseases at an alarming rate due to gut
microbiota dysbiosis, genetic and other environmental factors. Lactic acid bacteria (LAB) are …