The emergence of CRISPR-Cas systems has accelerated the development of gene editing
technologies, which are widely used in the life sciences. To improve the performance of …

Exosomes are extracellular vesicles that share components of their parent cells and are
attractive in biotechnology and biomedical research as potential disease biomarkers as well …

Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …

CRISPR-based nucleic acid detection methods are reported to facilitate rapid and sensitive
DNA detection. However, precise DNA detection at the single-base resolution and its wide …

The field of RNA nanotechnology has advanced rapidly during the past decade. A variety of
programmable RNA nanoparticles with defined shape, size, and stoichiometry have been …

The mortality rate of hemorrhagic African swine fever (ASF), which targets domestic pigs and
wild boars is caused by African swine fever virus (ASFV), can reach 100%. Since the first …

Biomimetic solid-state nanochannels enable new modalities for biosensing. In the last
decade, these nanofluidic architectures have been widely studied due to their rapid and …

Recent advancements in bioanalytical techniques have led to the development of novel and
robust diagnostic approaches that hold promise for providing optimal patient treatment …

Hybridization is a key molecular process in biology and biotechnology, but so far there is no
predictive model for accurately determining hybridization rate constants based on sequence …

This paper reviews methods for detecting proteins based on molecular digitization, ie, the
isolation and detection of single protein molecules or singulated ensembles of protein …