Colorectal cancer (CRC) is one of the leading causes of cancer mortality. Angiogenesis is a
rate-determining step in CRC development and metastasis. The balance of angiogenic and …

In the present study, preparation of poly (lactic-co-glycolic acid)(PLGA) nanoparticles coated
with chitosan (CS) conjugated to folic acid (FA) was applied to load Artemisia vulgaris L …

MAPK pathway sparkles with RTK activation, passes through subsequent downstream RAS-
RAF-MEK-ERK signaling cascades, with consequent direct and indirect CDK4/6 signaling …

Apoptosis signaling pathways, drug resistance, and metastasis are important targets to
develop new cancer treatments. We developed cholesterol-coated Poly (d, l-Lactide-co …

An inverse association between serum lycopene levels and the risk of cancers has been
pointed out by many prospective and retrospective epidemiological studies which prompted …

Angiogenesis is a vital step in many severe diseases such as cancer, diabetic retinopathy,
and rheumatoid arthritis. Sorafenib (SFB), a multi-tyrosine kinase inhibitor, has recently been …

Background Tumor-treating fields (TTFields) have been extensively used to treat various
cancers as well as glioblastoma multiforme (GBM), owing to their antimitotic effects …

In this contribution, we report a strategy to enhance the therapeutic action of the
chemotherapeutic Sorafenib (SRB) through its combination with a multifunctional β …

Introduction: Proteasomes are multi-subunit protein complexes responsible for protein
degradation in cells. Immunoproteasomes and intermediate proteasomes (together non …

Simple Summary In this study, we delve into a challenging aspect of breast cancer known as
triple-negative breast cancer (TNBC), which lacks effective treatment options due to its …