The first matrix metalloproteinase (MMP) was discovered in 1962 from the tail of a tadpole by
its ability to degrade collagen. As their name suggests, matrix metalloproteinases are …

Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that are
involved in the degradation of various proteins in the extracellular matrix (ECM). Typically …

Abstract Implication By understanding Matrix Metalloprotease (MMP) dysregulation from a
pan-cancer perspective, this study sheds light on the diagnostic potentials of MMPs across …

The epithelial‐mesenchymal transition (EMT) is a transformation process mandatory for the
local and distant progression of many malignant tumors, including hepatocellular carcinoma …

Membrane-type matrix metalloproteinases (MT-MMPs) form a subgroup of the matrix
metalloproteinase (MMP) family, and there are 6 MT-MMPs in humans. MT-MMPs are further …

Abstract Background Matrix metalloproteinases (MMPs) are a family of ubiquitously
expressed zinc-dependent endopeptidases with broad substrate specificity and strictly …

Matrix metalloproteases (MMPs) comprise a family of enzymes that cleave protein substrates
based on a conserved mechanism involving activation of an active site-bound water …

Matrix metalloproteinases (MMPs) are a large family of zinc-endopeptidases which play
important roles in multiple physiological and pathological processes. These enzymes are …

Colorectal cancer (CRC) develops by genetic and epigenetic alterations. However, the
molecular mechanisms underlying metastatic dissemination remain unclear and could …

The retina contains ganglion cells (RGCs) that respond selectively to objects moving in
particular directions. Individual members of a group of ON-OFF direction-selective RGCs …