[HTML][HTML] Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers
S Haddadzadegan, F Dorkoosh… - Advanced drug delivery …, 2022 - Elsevier
The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …
commercial point of view. In order to reach the systemic circulation after oral administration …
[HTML][HTML] Recent advancements on novel approaches of insulin delivery
S Karmakar, M Bhowmik, B Laha, S Manna - Medicine in Novel Technology …, 2023 - Elsevier
A large number of populations are living with diabetes, which is the most common endocrine
disorder which is classified into Type-I and Type-II diabetes. Diabetes is one of the listed …
disorder which is classified into Type-I and Type-II diabetes. Diabetes is one of the listed …
A comprehensive review of the evolution of insulin development and its delivery method
The year 2021 marks the 100th anniversary of the momentous discovery of insulin. Through
years of research and discovery, insulin has evolved from poorly defined crude extracts of …
years of research and discovery, insulin has evolved from poorly defined crude extracts of …
Permeability of buccal mucosa
The buccal mucosa provides an alternative route of drug delivery that can be more
beneficial compared to other administration routes. Although numerous studies and reviews …
beneficial compared to other administration routes. Although numerous studies and reviews …
Design and evaluation of hydrophobic ion paired insulin loaded self micro-emulsifying drug delivery system for oral delivery
Despite several novel and innovative approaches, clinical translation of oral insulin delivery
into commercially viable treatment is still challenging due to its poor absorption and rapid …
into commercially viable treatment is still challenging due to its poor absorption and rapid …
Alternative methotrexate oral formulation: enhanced aqueous solubility, bioavailability, photostability, and permeability
The poor aqueous solubility and/or permeability and thereby limited bioavailability largely
restricts the pharmaco-therapeutic implications of potent anticancer drugs such as …
restricts the pharmaco-therapeutic implications of potent anticancer drugs such as …
Oral mucosa models to evaluate drug permeability
E Mazzinelli, I Favuzzi, A Arcovito, R Castagnola… - Pharmaceutics, 2023 - mdpi.com
Due to its numerous advantages, such as excellent drug accessibility, rapid absorption, and
bypass of first-pass metabolism, the route of drug administration that involves crossing the …
bypass of first-pass metabolism, the route of drug administration that involves crossing the …
Non-invasive delivery of Insulin for breaching hindrances against Diabetes
Insulin is recognized as a crucial weapon in managing diabetes. Subcutaneous (sc)
injections are the traditional approach for insulin administration, which usually have many …
injections are the traditional approach for insulin administration, which usually have many …
[HTML][HTML] Buccal Absorption of Biopharmaceutics Classification System III Drugs: Formulation Approaches and Mechanistic Insights
R Sabra, D Kirby, V Chouk, K Malgorzata… - Pharmaceutics, 2024 - mdpi.com
Buccal drug delivery emerges as a promising strategy to enhance the absorption of drugs
classified under the Biopharmaceutics Classification System (BCS) Class III, characterized …
classified under the Biopharmaceutics Classification System (BCS) Class III, characterized …
[PDF][PDF] Design and Evaluation of Hydrophobic Ion Paired Insulin Loaded Self Micro-Emulsifying Drug Delivery System for Oral Delivery. Pharmaceutics 2023, 15, 1973
Despite several novel and innovative approaches, clinical translation of oral insulin delivery
into commercially viable treatment is still challenging due to its poor absorption and rapid …
into commercially viable treatment is still challenging due to its poor absorption and rapid …