Cardiac mechano-electric coupling: acute effects of mechanical stimulation on heart rate and rhythm
The heart is vital for biological function in almost all chordates, including humans. It beats
continually throughout our life, supplying the body with oxygen and nutrients while removing …
continually throughout our life, supplying the body with oxygen and nutrients while removing …
[HTML][HTML] Structure and function of the ventricular tachycardia isthmus
Highlights•Postinfarction ventricular tachycardia (VT) caused by a reentrant circuit is an
important clinical problem.•Catheter ablation may not prevent VT because of difficulty in …
important clinical problem.•Catheter ablation may not prevent VT because of difficulty in …
Tunable human myocardium derived decellularized extracellular matrix for 3D bioprinting and cardiac tissue engineering
The generation of 3D tissue constructs with multiple cell types and matching mechanical
properties remains a challenge in cardiac tissue engineering. Recently, 3D bioprinting has …
properties remains a challenge in cardiac tissue engineering. Recently, 3D bioprinting has …
MedalCare-XL: 16,900 healthy and pathological synthetic 12 lead ECGs from electrophysiological simulations
Mechanistic cardiac electrophysiology models allow for personalized simulations of the
electrical activity in the heart and the ensuing electrocardiogram (ECG) on the body surface …
electrical activity in the heart and the ensuing electrocardiogram (ECG) on the body surface …
Personalized cardiac computational models: from clinical data to simulation of infarct-related ventricular tachycardia
A Lopez-Perez, R Sebastian, M Izquierdo… - Frontiers in …, 2019 - frontiersin.org
In the chronic stage of myocardial infarction, a significant number of patients develop life-
threatening ventricular tachycardias (VT) due to the arrhythmogenic nature of the remodeled …
threatening ventricular tachycardias (VT) due to the arrhythmogenic nature of the remodeled …
Biowire model of interstitial and focal cardiac fibrosis
Myocardial fibrosis is a severe global health problem due to its prevalence in all forms of
cardiac diseases and direct role in causing heart failure. The discovery of efficient antifibrotic …
cardiac diseases and direct role in causing heart failure. The discovery of efficient antifibrotic …
Predicting risk of sudden cardiac death in patients with cardiac sarcoidosis using multimodality imaging and personalized heart modeling in a multivariable classifier
Cardiac sarcoidosis (CS), an inflammatory disease characterized by formation of
granulomas in the heart, is associated with high risk of sudden cardiac death (SCD) from …
granulomas in the heart, is associated with high risk of sudden cardiac death (SCD) from …
Air pollution and cardiac arrhythmias: from epidemiological and clinical evidences to cellular electrophysiological mechanisms
Cardiovascular disease is the leading cause of death worldwide and kills over 17 million
people per year. In the recent decade, growing epidemiological evidence links air pollution …
people per year. In the recent decade, growing epidemiological evidence links air pollution …
From evidence-based medicine to digital twin technology for predicting ventricular tachycardia in ischaemic cardiomyopathy
AGW de Lepper, CMA Buck… - Journal of the …, 2022 - royalsocietypublishing.org
Survivors of myocardial infarction are at risk of life-threatening ventricular tachycardias (VTs)
later in their lives. Current guidelines for implantable cardioverter defibrillators (ICDs) …
later in their lives. Current guidelines for implantable cardioverter defibrillators (ICDs) …
A myocardial infarct border-zone-on-a-chip demonstrates distinct regulation of cardiac tissue function by an oxygen gradient
After a myocardial infarction, the boundary between the injured, hypoxic tissue and the
adjacent viable, normoxic tissue, known as the border zone, is characterized by an oxygen …
adjacent viable, normoxic tissue, known as the border zone, is characterized by an oxygen …