Unique roles of gold nanoparticles in drug delivery, targeting and imaging applications

FY Kong, JW Zhang, RF Li, ZX Wang, WJ Wang… - Molecules, 2017 - mdpi.com
Nanotechnology has become more and more potentially used in diagnosis or treatment of
diseases. Advances in nanotechnology have led to new and improved nanomaterials in …

Functionalized gold nanoparticles and their biomedical applications

PM Tiwari, K Vig, VA Dennis, SR Singh - Nanomaterials, 2011 - mdpi.com
Metal nanoparticles are being extensively used in various biomedical applications due to
their small size to volume ratio and extensive thermal stability. Gold nanoparticles (GNPs) …

Drug delivery and nanoparticles: applications and hazards

WH De Jong, PJA Borm - International journal of nanomedicine, 2008 - Taylor & Francis
The use of nanotechnology in medicine and more specifically drug delivery is set to spread
rapidly. Currently many substances are under investigation for drug delivery and more …

Cancer‐targeting nanoparticles for combinatorial nucleic acid delivery

HJ Vaughan, JJ Green, SY Tzeng - Advanced Materials, 2020 - Wiley Online Library
Nucleic acids are a promising type of therapeutic for the treatment of a wide range of
conditions, including cancer, but they also pose many delivery challenges. For efficient and …

Particle size-dependent organ distribution of gold nanoparticles after intravenous administration

WH De Jong, WI Hagens, P Krystek, MC Burger… - Biomaterials, 2008 - Elsevier
A kinetic study was performed to determine the influence of particle size on the in vivo tissue
distribution of spherical-shaped gold nanoparticles in the rat. Gold nanoparticles were …

Biodistribution of colloidal gold nanoparticles after intravenous administration: effect of particle size

G Sonavane, K Tomoda, K Makino - Colloids and Surfaces B: Biointerfaces, 2008 - Elsevier
Purpose of the present research work was to evaluate the biological distribution of differently
size gold nanoparticles (NP) up on intravenous administration in mice. Another objective …

The forthcoming applications of gold nanoparticles in drug and gene delivery systems

D Pissuwan, T Niidome, MB Cortie - Journal of controlled release, 2011 - Elsevier
The unique optical, chemical, and biological properties of gold nanoparticles have resulted
in them becoming of clinical interest in several applications including drug and gene …

PEG-modified gold nanorods with a stealth character for in vivo applications

T Niidome, M Yamagata, Y Okamoto, Y Akiyama… - Journal of Controlled …, 2006 - Elsevier
Gold nanorods prepared in hexadecyltrimethylammonium bromide (CTAB) solution are
expected to provide novel materials for photothermal therapy and photo-controlled drug …

Use of size and a copolymer design feature to improve the biodistribution and the enhanced permeability and retention effect of doxorubicin-loaded mesoporous silica …

H Meng, M Xue, T Xia, Z Ji, DY Tarn, JI Zink, AE Nel - ACS nano, 2011 - ACS Publications
A key challenge for improving the efficacy of passive drug delivery to tumor sites by a
nanocarrier is to limit reticuloendothelial system uptake and to maximize the enhanced …

Monolayer coated gold nanoparticles for delivery applications

S Rana, A Bajaj, R Mout, VM Rotello - Advanced drug delivery reviews, 2012 - Elsevier
Gold nanoparticles (AuNPs) provide attractive vehicles for delivery of drugs, genetic
materials, proteins, and small molecules. AuNPs feature low core toxicity coupled with the …