The function of fish cytokines
J Zou, CJ Secombes - Biology, 2016 - mdpi.com
What is known about the biological activity of fish cytokines is reviewed. Most of the
functional studies performed to date have been in teleost fish, and have focused on the …
functional studies performed to date have been in teleost fish, and have focused on the …
Fish cytokines: current research and applications
M Sakai, J Hikima, T Kono - Fisheries Science, 2021 - Springer
Cytokines are low molecular weight glycoproteins involved in the regulation of the immune
system, and more than 100 cytokines have hitherto been identified in humans. Cytokines …
system, and more than 100 cytokines have hitherto been identified in humans. Cytokines …
Function of CSF1 and IL34 in macrophage homeostasis, inflammation, and cancer
WY Lin, D Xu, CD Austin, P Caplazi, K Senger… - Frontiers in …, 2019 - frontiersin.org
Colony-stimulating factor 1 (CSF1) and interleukin 34 (IL34) signal via the CSF1 receptor to
regulate macrophage differentiation. Studies in IL34-or CSF1-deficient mice have revealed …
regulate macrophage differentiation. Studies in IL34-or CSF1-deficient mice have revealed …
B lymphocytes from early vertebrates have potent phagocytic and microbicidal abilities
J Li, DR Barreda, YA Zhang, H Boshra, AE Gelman… - Nature …, 2006 - nature.com
The present paradigm dictates that phagocytosis is accomplished mainly by'professional'
phagocytes (such as macrophages and monocytes), whereas B cells lack phagocytic …
phagocytes (such as macrophages and monocytes), whereas B cells lack phagocytic …
Mechanisms of fish macrophage antimicrobial immunity
L Grayfer, B Kerimoglu, A Yaparla… - Frontiers in …, 2018 - frontiersin.org
Overcrowding conditions and temperatures shifts regularly manifest in large-scale infections
of farmed fish, resulting in economic losses for the global aquaculture industries. Increased …
of farmed fish, resulting in economic losses for the global aquaculture industries. Increased …
Polarization of immune responses in fish: The 'macrophages first'point of view
In this review, we support taking polarized immune responses in teleost fish from a
'macrophage first'point of view, a hypothesis that reverts the dichotomous T helper (TH) 1 …
'macrophage first'point of view, a hypothesis that reverts the dichotomous T helper (TH) 1 …
Insights into the role of CSF1R in the central nervous system and neurological disorders
B Hu, S Duan, Z Wang, X Li, Y Zhou… - Frontiers in Aging …, 2021 - frontiersin.org
The colony-stimulating factor 1 receptor (CSF1R) is a key tyrosine kinase transmembrane
receptor modulating microglial homeostasis, neurogenesis, and neuronal survival in the …
receptor modulating microglial homeostasis, neurogenesis, and neuronal survival in the …
Antimicrobial responses of teleost phagocytes and innate immune evasion strategies of intracellular bacteria
L Grayfer, JW Hodgkinson, M Belosevic - Developmental & Comparative …, 2014 - Elsevier
During infection, macrophage lineage cells eliminate infiltrating pathogens through a battery
of antimicrobial responses, where the efficacy of these innate immune responses is pivotal …
of antimicrobial responses, where the efficacy of these innate immune responses is pivotal …
Conventional apoptosis assays using propidium iodide generate a significant number of false positives that prevent accurate assessment of cell death
AM Rieger, BE Hall, LM Schang, DR Barreda - Journal of immunological …, 2010 - Elsevier
The advent of flow cytometry-based applications has significantly impacted the study of
cellular apoptosis. Propidium iodide (PI) is a commonly used viability stain in these studies …
cellular apoptosis. Propidium iodide (PI) is a commonly used viability stain in these studies …
Two macrophage colony-stimulating factor genes exist in fish that differ in gene organization and are differentially expressed
Abstract Mammalian macrophage CSF (MCSF; CSF-1) is the primary regulator of the
mononuclear phagocyte lineage. We, for the first time, report the complete sequencing of …
mononuclear phagocyte lineage. We, for the first time, report the complete sequencing of …