Clinical intervention using focused ultrasound (FUS) stimulation of the brain in diverse neurological disorders

H Baek, D Lockwood, EJ Mason, E Obusez… - Frontiers in …, 2022 - frontiersin.org
Various surgical techniques and pharmaceutical treatments have been developed to
improve the current technologies of treating brain diseases. Focused ultrasound (FUS) is a …

[HTML][HTML] Tremor in Parkinson's disease: from pathophysiology to advanced therapies

AH Abusrair, W Elsekaily, S Bohlega - Tremor and Other …, 2022 - ncbi.nlm.nih.gov
Background: Tremor is one of the most prevalent symptoms in Parkinson's Disease (PD).
The progression and management of tremor in PD can be challenging, as response to …

Bilateral focused ultrasound thalamotomy for essential tremor (BEST‐FUS phase 2 trial)

C Iorio‐Morin, K Yamamoto, C Sarica… - Movement …, 2021 - Wiley Online Library
Background In patients with medically refractory essential tremor, unilateral magnetic
resonance–guided focused ultrasound thalamotomy can improve contralateral tremor …

Magnetic resonance imaging–guided focused ultrasound thalamotomy for essential tremor: 5-year follow-up results

GR Cosgrove, N Lipsman, AM Lozano, JW Chang… - Journal of …, 2022 - thejns.org
OBJECTIVE The objective of this study was to evaluate, at 4 and 5 years posttreatment, the
long-term safety and efficacy of unilateral MRI-guided focused ultrasound (MRgFUS) …

The return of the lesion for localization and therapy

J Joutsa, N Lipsman, A Horn, GR Cosgrove, MD Fox - Brain, 2023 - academic.oup.com
Historically, pathological brain lesions provided the foundation for localization of symptoms
and therapeutic lesions were used as a treatment for brain diseases. New medications …

Safety and efficacy of staged, bilateral focused ultrasound thalamotomy in essential tremor: an open-label clinical trial

MG Kaplitt, V Krishna, HM Eisenberg, WJ Elias… - JAMA …, 2024 - jamanetwork.com
Importance Unilateral magnetic resonance–guided focused ultrasound ablation of ventralis
intermedius nucleus of the thalamus for essential tremor reduces tremor on 1 side, but …

[HTML][HTML] Safety of bilateral staged magnetic resonance‐guided focused ultrasound thalamotomy for essential tremor

N Scantlebury, CR Rohringer, JS Rabin… - Movement Disorders …, 2023 - ncbi.nlm.nih.gov
Staged, open-surgical lesioning of the thalamic ventral intermediate nucleus to abate
medication-refractory essential tremor (mrET) has been historically associated with a high …

Cognitive effects of unilateral thalamotomy for tremor: a meta-analysis

CR Rohringer, IJ Sewell, S Gandhi, J Isen… - Brain …, 2022 - academic.oup.com
Tremor is a debilitating symptom that can lead to functional impairment. Pharmacotherapy is
often successful, but up to 50% of patients are resistant to medications or cannot tolerate …

Double lesion MRgFUS treatment of essential tremor targeting the thalamus and posterior sub-thalamic area: preliminary study with two year follow-up

A Jameel, W Gedroyc, D Nandi, B Jones… - British Journal of …, 2022 - Taylor & Francis
Background MR-guided focused ultrasound (MRgFUS) is an effective treatment for essential
tremor (ET). However, the optimal intracranial target sites remain to be determined …

Update in the clinical application of focused ultrasound

E Natera-Villalba, M Matarazzo… - Current Opinion in …, 2022 - journals.lww.com
Update in the clinical application of focused ultrasound : Current Opinion in Neurology Update in
the clinical application of focused ultrasound : Current Opinion in Neurology Log in or Register …