Lipids and prostate cancer

J Suburu, YQ Chen - Prostaglandins & other lipid mediators, 2012 - Elsevier
The role of lipid metabolism has gained particular interest in prostate cancer research. A
large body of literature has outlined the unique upregulation of de novo lipid synthesis in …

Methylglyoxal-derived stress: an emerging biological factor involved in the onset and progression of cancer

A Bellahcène, MJ Nokin, V Castronovo… - Seminars in cancer …, 2018 - Elsevier
Cancer is a disease characterised by uncontrolled growth and proliferation of cells. Tumours
primarily show a higher rate of glucose uptake for lactate production even in the presence of …

SARAF inactivates the store operated calcium entry machinery to prevent excess calcium refilling

R Palty, A Raveh, I Kaminsky, R Meller, E Reuveny - Cell, 2012 - cell.com
Store operated calcium entry (SOCE) is a principal cellular process by which cells regulate
basal calcium, refill intracellular Ca 2+ stores, and execute a wide range of specialized …

Lipidomic profiling of clinical prostate cancer reveals targetable alterations in membrane lipid composition

LM Butler, CY Mah, J Machiels, AD Vincent, S Irani… - Cancer research, 2021 - AACR
Dysregulated lipid metabolism is a prominent feature of prostate cancer that is driven by
androgen receptor (AR) signaling. Here we used quantitative mass spectrometry to define …

Salivary exosomal PSMA7: a promising biomarker of inflammatory bowel disease

X Zheng, F Chen, Q Zhang, Y Liu, P You, S Sun… - Protein & …, 2017 - academic.oup.com
Inflammatory bowel disease (IBD) is an intestinal immune-dysfunctional disease worldwide
whose prevalence increasing in Asia including China. It is a chronic disease of the …

[HTML][HTML] A signature of tumor immune microenvironment genes associated with the prognosis of non‑small cell lung cancer

J Li, X Li, C Zhang, C Zhang… - Oncology reports, 2020 - spandidos-publications.com
Establishing a prognostic genetic signature closely related to the tumor immune
microenvironment (TIME) to predict clinical outcomes is necessary. Using the Gene …

In vivo CRISPR screens reveal Serpinb9 and Adam2 as regulators of immune therapy response in lung cancer

D Dervovic, AA Malik, ELY Chen, M Narimatsu… - Nature …, 2023 - nature.com
How the genetic landscape governs a tumor's response to immunotherapy remains poorly
understood. To assess the immune-modulatory capabilities of 573 genes associated with …

[HTML][HTML] Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations

S Lorenz, T Barøy, J Sun, T Nome, D Vodák, JC Bryne… - Oncotarget, 2016 - ncbi.nlm.nih.gov
In contrast to many other sarcoma subtypes, the chaotic karyotypes of osteosarcoma have
precluded the identification of pathognomonic translocations. We here report hundreds of …

Oncogenic role of tumor necrosis factor α-induced protein 8 (TNFAIP8)

S Niture, X Dong, E Arthur, U Chimeh, SS Niture… - Cells, 2018 - mdpi.com
Tumor necrosis factor (TNF)-α-induced protein 8 (TNFAIP8) is a founding member of the
TIPE family, which also includes TNFAIP8-like 1 (TIPE1), TNFAIP8-like 2 (TIPE2), and …

Differential gene expression and weighted correlation network dynamics in high-throughput datasets of prostate cancer

T Mohammad, P Singh, DS Jairajpuri… - Frontiers in …, 2022 - frontiersin.org
Precision oncology is an absolute need today due to the emergence of treatment resistance
and heterogeneity among cancerous profiles. Target-propelled cancer therapy is one of the …