Background Although great achievements have been made in the field of cancer therapy,
chemotherapy and radiotherapy remain the mainstay cancer therapeutic modalities …

Nrf2 is a basic region leucine-zipper transcription factor that plays a pivotal role in the
coordinated gene expression of antioxidant and detoxifying enzymes, promoting cell …

The increase in human life expectancy has become a challenge to reduce the deleterious
consequences of aging. Nowadays, an increasing number of the population suffer from age …

The lack of therapy and the failure of existing therapy has been a challenge for clinicians in
treating various cancers. Doxorubicin, 5-fluorouracil, cisplatin, and paclitaxel are the first-line …

Virus‐induced oxidative stress plays a critical role in the viral life cycle as well as the
pathogenesis of viral diseases. In response to reactive oxygen species (ROS) generation by …

Anticancer drug like Cisplatin are associated with serious problem like nephrotoxicity. The
effect of Kaempferol is a plant-derived flavonoid compound. The present work evaluated the …

The nuclear factor E2-related factor 2 (Nrf2) plays an important role in cellular protection
against cancer, renal, pulmonary, cardiovascular and neurodegenerative diseases where …

Acute kidney injury (AKI) is an important health problem, affecting 13.3 million
individuals/year. It is associated with increased mortality, mainly in low-and middle-income …

Acute renal failure is a serious complication of the anticancer drug cisplatin. The potential
role of baicalein, a naturally occurring bioflavonoid on cisplatin-induced renal injury is …

(E)-β-caryophyllene (BCP) is a natural sesquiterpene found in many essential oils of spice
(best known for contributing to the spiciness of black pepper) and food plants with …