[HTML][HTML] Non-alcoholic fatty liver disease and psoriasis: So far, so near

G Ganzetti, A Campanati, A Offidani - World journal of hepatology, 2015 - ncbi.nlm.nih.gov
Psoriasis is a chronic inflammatory immune-mediated skin diseases which is frequently
associated to comorbidities. Non-alcoholic fatty liver disease (NAFLD) is defined as an …

Obestatin as a key regulator of metabolism and cardiovascular function with emerging therapeutic potential for diabetes

E Cowan, KJ Burch, BD Green… - British Journal of …, 2016 - Wiley Online Library
Obestatin is a 23‐amino acid C‐terminally amidated gastrointestinal peptide derived from
preproghrelin and which forms an α helix. Although obestatin has a short biological half‐life …

How adiponectin, leptin, and ghrelin orchestrate together and correlate with the severity of nonalcoholic fatty liver disease

MV Machado, J Coutinho, F Carepa… - European journal of …, 2012 - journals.lww.com
Background Adipose tissue contributes to nonalcoholic fatty liver disease (NAFLD), being a
source of fatty acids and cytokines such as leptin and adiponectin, and regulating ghrelin …

[HTML][HTML] Ghrelin attenuated lipotoxicity via autophagy induction and nuclear factor-κB inhibition

Y Mao, J Cheng, F Yu, H Li, C Guo, X Fan - Cellular Physiology and …, 2015 - karger.com
Background/Aims: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic
liver disease worldwide. Autophagy is associated with NAFLD. Ghrelin is a gut hormone with …

Changes in obestatin gene and GPR39 receptor expression in peripheral tissues of rat models of obesity, type 1 and type 2 diabetes: 肥胖, 1 型与2 型糖尿病大鼠模型 …

PA Kolodziejski, E Pruszynska‐Oszmalek… - Journal of …, 2017 - Wiley Online Library
背景: 肥胖抑制素在调节食物摄入与能量消耗方面具有重要作用, 但是肥胖抑制素与GPR39
受体在1 型与2 型糖尿病(T1DM 与T2DM) 中的作用目前尚未十分明确. 当前这项研究的目的是 …

Effect of desacyl ghrelin, obestatin and related peptides on triglyceride storage, metabolism and GHSR signaling in 3T3‐L1 adipocytes

P Miegueu, D St Pierre, F Broglio… - Journal of cellular …, 2011 - Wiley Online Library
Abstract Acyl‐ghrelin (AG), desacyl‐ghrelin (DAG) and obestatin are all derived from the
same gene transcript; however their plasma levels do not necessarily change in parallel …

Diagnostic accuracy of acyl-ghrelin and it association with non-alcoholic fatty liver disease in type 2 diabetic patients

G Mykhalchyshyn, N Kobyliak, P Bodnar - Journal of Diabetes & Metabolic …, 2015 - Springer
Background Ghrelin is a hormone produced mainly by the cells lining the fundus of the
stomach, which is involved in regulation of lipid and glucose metabolism. Two major forms of …

Molecular and cellular mechanisms underlying the hepatoprotective role of ghrelin against NAFLD progression

C Tuero, S Becerril, S Ezquerro, G Neira… - Journal of physiology …, 2023 - Springer
The underlying mechanisms for the development and progression of nonalcoholic fatty liver
disease (NAFLD) are complex and multifactorial. Within the last years, experimental and …

[HTML][HTML] Exogenous administration of unacylated ghrelin attenuates hepatic steatosis in high-fat diet-fed rats by modulating glucose homeostasis, lipogenesis …

S Alharbi - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Low levels of unacylated ghrelin (UAG) and a higher ratio of acylated ghrelin (AG)/UAG in
obesity are associated with non-alcoholic fatty liver disease (NAFLD). This study tested the …

Diet-induced fasting ghrelin elevation reflects the recovery of insulin sensitivity and visceral adiposity regression

G Tsaban, A Yaskolka Meir, H Zelicha… - The Journal of …, 2022 - academic.oup.com
Context Lower fasting ghrelin levels (FGL) are associated with obesity and metabolic
syndrome. Objective We aimed to explore the dynamics of FGL during weight loss and its …