The Drosophila Hippo pathway transcription factor Scalloped and its co-factors alter each other's chromatin binding dynamics and transcription in vivo
SA Manning, B Kroeger, Q Deng, E Brooks… - Developmental Cell, 2024 - cell.com
The Hippo pathway is an important regulator of organ growth and cell fate. The major
mechanism by which Hippo is known to control transcription is by dictating the nucleo …
mechanism by which Hippo is known to control transcription is by dictating the nucleo …
Local weakening of cell-ECM adhesion triggers basal tissue folding via changes in cell shape, actomyosin organization and E-cad levels
A Valencia-Exposito, N Khalilgharibi, Y Mao… - bioRxiv, 2024 - biorxiv.org
During embryogenesis, epithelial sheets sculpt organs by folding, either apically or basally,
into complex 3D structures. Given the presence of actomyosin networks and cell adhesion …
into complex 3D structures. Given the presence of actomyosin networks and cell adhesion …
Sinuous Is a Claudin Required for Locust Molt in Locusta migratoria
Y Zhang, H Li, Q Lan, X Liu, H Wu, J Zhang, X Zhao… - Genes, 2024 - mdpi.com
The epidermal cells of insects are polarized epithelial cells that play a pivotal role in the
insect's molting process. Sinuous, a pivotal structural protein involved in the formation of …
insect's molting process. Sinuous, a pivotal structural protein involved in the formation of …
Oncogenic signaling in the adult Drosophila prostate-like accessory gland leads to activation of a conserved pro-tumorigenic program, in the absence of proliferation.
SJ Church, AJ Pulianmackal, JA Dixon, LV Loftus… - bioRxiv, 2024 - biorxiv.org
Drosophila models for tumorigenesis and metastasis have revealed conserved mechanisms
of signaling that are also involved in mammalian cancer. Many of these models use the …
of signaling that are also involved in mammalian cancer. Many of these models use the …
A multicellular actin star network underpins epithelial organization and connectivity
Epithelial tissues serve as physical barriers against various external pressures yet
remarkably maintain structural stability. Various cellular apparatus including bicellular …
remarkably maintain structural stability. Various cellular apparatus including bicellular …
Compressive stress drives morphogenetic apoptosis
T Merle, M Cazales, R Bouzignac, B Ronsin… - bioRxiv, 2024 - biorxiv.org
Tissues and organs are constantly submitted to physical stress, including compression,
stretching, shear stress. These physical constraints can influence fundamental processes …
stretching, shear stress. These physical constraints can influence fundamental processes …
[HTML][HTML] Live imaging basement membrane assembly under the pupal notum epithelium
TM Mehaffey, CA Hecht, JS White… - Micropublication …, 2024 - ncbi.nlm.nih.gov
Basement membranes are sheet-like extracellular matrices containing Collagen IV, and they
are conserved across the animal kingdom. Basement membranes usually line the basal …
are conserved across the animal kingdom. Basement membranes usually line the basal …