The 5th edition of the World Health Organization classification of haematolymphoid tumours: myeloid and histiocytic/dendritic neoplasms
The upcoming 5th edition of the World Health Organization (WHO) Classification of
Haematolymphoid Tumours is part of an effort to hierarchically catalogue human cancers …
Haematolymphoid Tumours is part of an effort to hierarchically catalogue human cancers …
Acute lymphoblastic leukaemia
F Malard, M Mohty - The Lancet, 2020 - thelancet.com
Acute lymphoblastic leukaemia develops in both children and adults, with a peak incidence
between 1 year and 4 years. Most acute lymphoblastic leukaemia arises in healthy …
between 1 year and 4 years. Most acute lymphoblastic leukaemia arises in healthy …
International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data
The classification of myeloid neoplasms and acute leukemias was last updated in 2016
within a collaboration between the World Health Organization (WHO), the Society for …
within a collaboration between the World Health Organization (WHO), the Society for …
Microfluidics-free single-cell genomics with templated emulsification
IC Clark, KM Fontanez, RH Meltzer, Y Xue… - Nature …, 2023 - nature.com
Current single-cell RNA-sequencing approaches have limitations that stem from the
microfluidic devices or fluid handling steps required for sample processing. We develop a …
microfluidic devices or fluid handling steps required for sample processing. We develop a …
Genomes for kids: the scope of pathogenic mutations in pediatric cancer revealed by comprehensive DNA and RNA sequencing
S Newman, J Nakitandwe, CA Kesserwan, EM Azzato… - Cancer discovery, 2021 - AACR
Genomic studies of pediatric cancer have primarily focused on specific tumor types or high-
risk disease. Here, we used a three-platform sequencing approach, including whole …
risk disease. Here, we used a three-platform sequencing approach, including whole …
PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia
Recent genomic studies have identified chromosomal rearrangements defining new
subtypes of B-progenitor acute lymphoblastic leukemia (B-ALL), however many cases lack a …
subtypes of B-progenitor acute lymphoblastic leukemia (B-ALL), however many cases lack a …
Advances in the diagnosis and treatment of pediatric acute lymphoblastic leukemia
H Inaba, CH Pui - Journal of clinical medicine, 2021 - mdpi.com
The outcomes of pediatric acute lymphoblastic leukemia (ALL) have improved remarkably
during the last five decades. Such improvements were made possible by the incorporation of …
during the last five decades. Such improvements were made possible by the incorporation of …
Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes
Abstract CD4+ effector lymphocytes (Teff) are traditionally classified by the cytokines they
produce. To determine the states that Teff cells actually adopt in frontline tissues in vivo, we …
produce. To determine the states that Teff cells actually adopt in frontline tissues in vivo, we …
A new genomic framework to categorize pediatric acute myeloid leukemia
Recent studies on pediatric acute myeloid leukemia (pAML) have revealed pediatric-specific
driver alterations, many of which are underrepresented in the current classification schemas …
driver alterations, many of which are underrepresented in the current classification schemas …
Single-cell multiomic analysis identifies regulatory programs in mixed-phenotype acute leukemia
JM Granja, S Klemm, LM McGinnis, AS Kathiria… - Nature …, 2019 - nature.com
Identifying the causes of human diseases requires deconvolution of abnormal molecular
phenotypes spanning DNA accessibility, gene expression and protein abundance,–. We …
phenotypes spanning DNA accessibility, gene expression and protein abundance,–. We …