Cardiac arrest occurs at a higher rate in children with heart disease than in healthy children.
Pediatric basic life support and advanced life support guidelines focus on delivering high …

Background Children with congenital heart disease often undergo heart surgery at a young
age. They are at risk for postoperative low cardiac output syndrome (LCOS) or death …

Purpose Septic shock is a leading cause of death among critically ill patients, in particular
when complicated by acute kidney injury (AKI). Small experimental and human clinical …

Context Polymyxin B fiber column is a medical device designed to reduce blood endotoxin
levels in sepsis. Gram-negative–induced abdominal sepsis is likely associated with high …

Objectives: We conducted a randomized controlled trial of the effects of remote ischemic
preconditioning (RIPC) in children undergoing repair of congenital heart defects …

Rationale: No medical intervention has been identified that decreases acute kidney injury
and improves renal outcome at 1 year after cardiac surgery. Objectives: To determine …

OBJECTIVES: Neurologic deficits are common after the Norwood procedure for hypoplastic
left heart syndrome. Because of the association of deep hypothermic circulatory arrest with …

BACKGROUND: Remote perconditioning has been proved to reduce myocardial infarction
and improve ventricular function in vivo. This study aims to determine the protection of …

Background—Steroid administration during cardiopulmonary bypass is thought to improve
cardiopulmonary function by modulating bypass-related inflammation. This study was …

Background Recent randomized trials have not found that polymyxin B hemoperfusion (PMX-
HP) improves outcomes for patients with sepsis. However, it remains unclear whether the …