In the drug discovery setting, undesirable ADMET properties of a pharmacophore with good
predictive power obtained after a tedious drug discovery and development process may …

Pharmaceutical drug analysis (PDA), besides quantifying drugs and related substances
(RS), can enrich drug discovery (DD) by suggesting new leads. PDA may be extended …

Montelukast sodium (MLS) is a leukotriene receptor antagonist that relieves asthma,
bronchospasm, allergic rhinitis, and urticaria. A simple, robust, and stability‐indicating …

Arginase catalyzes the hydrolysis of l-arginine into l-ornithine and urea, acting as a key
enzyme in the biosynthesis of polyamines. Leishmania growth and survival is dependent on …

Forced degradation studies have been used to simplify analytical methodology development
and achieve a deeper knowledge about the inherent stability of active pharmaceutical …

Visible light promoted domino synthesis of 2-aryl benzimidazoles is reported through the
reaction of ortho-phenylenediamines and arylmethyl amines under aerobic conditions. The …

Cordyceps sinensis (CS) has been widely used as a dietary supplement or traditional
medicine for the prevention, treatment, and prognostication of various diseases, because of …

The present study focused upon the forced degradation behaviour of fosamprenavir (FPV),
an antiretroviral drug. A total of six degradation products (DPs) were separated on a non …

Chemicals have multiple effects in biological systems. Because their on-target effects
dominate the output, their off-target effects are often overlooked and can sometimes cause …

The purpose of this study was to enhance the stability of montelukast and levocetirizine for
the development of a fixed-dose combination (FDC) monolayer tablet. To evaluate the …