It is now well-established that early life adversity (ELA) predisposes individuals to develop
several neuropsychiatric conditions, including anxiety disorders, and major depressive …

Substance use disorder (SUD) is a global public health concern that affects millions of
people worldwide. Considering current research, addiction has been noted as the last stage …

Adolescence is a period of profound developmental changes, which run the gamut from
behavioral and neural to physiological and hormonal. It is also a time at which there is an …

There is an urgent need to develop more effective treatments for stress-related illnesses,
which include depression, post-traumatic stress disorder, and anxiety. We view animal …

Depression is a complex and highly heterogeneous disorder which diagnosis is based on
an exceedingly variable set of clinical symptoms. Current treatments focus almost …

Background Stress-induced illnesses, like major depression, are among the leading causes
of disability across the world. Consequently, there is a dire need for the validation of …

Ketamine was first synthesized in the early 1960s in search for anesthetic compounds and
has been a mainstay for anesthesia since its approval by the United States Food and Drug …

The impact of psychosocial stressors on cardiovascular health in women is of growing
interest in both the popular and scientific literature. Rodent models are useful for providing …

Background Ketamine (KET) is administered to manage major depression in adolescent
patients. However, the long-term effects of juvenile KET exposure on memory-related tasks …

S-ketamine is approved for treatment-resistant patients with depression and adult patients
with suicide behavior. While ketamine is therapeutically beneficial in adults, there is a dearth …