Acclimatization and adaptive capacity of marine species in a changing ocean

SA Foo, M Byrne - Advances in marine biology, 2016 - Elsevier
To persist in an ocean changing in temperature, pH and other stressors related to climate
change, many marine species will likely need to acclimatize or adapt to avoid extinction. If …

Environmental epigenetics in zebrafish

V Cavalieri, G Spinelli - Epigenetics & chromatin, 2017 - Springer
It is widely accepted that the epigenome can act as the link between environmental cues,
both external and internal, to the organism and phenotype by converting the environmental …

Discovery and characterization of variance QTLs in human induced pluripotent stem cells

AK Sarkar, PY Tung, JD Blischak, JE Burnett, YI Li… - PLoS …, 2019 - journals.plos.org
Quantification of gene expression levels at the single cell level has revealed that gene
expression can vary substantially even across a population of homogeneous cells …

Mechanisms of mutational robustness in transcriptional regulation

JL Payne, A Wagner - Frontiers in Genetics, 2015 - frontiersin.org
Robustness is the invariance of a phenotype in the face of environmental or genetic change.
The phenotypes produced by transcriptional regulatory circuits are gene expression patterns …

Comparative developmental transcriptomics reveals rewiring of a highly conserved gene regulatory network during a major life history switch in the sea urchin genus …

JW Israel, ML Martik, M Byrne, EC Raff, RA Raff… - PLoS …, 2016 - journals.plos.org
The ecologically significant shift in developmental strategy from planktotrophic (feeding) to
lecithotrophic (nonfeeding) development in the sea urchin genus Heliocidaris is one of the …

Differences in performance and transcriptome‐wide gene expression associated with Rhagoletis (Diptera: Tephritidae) larvae feeding in alternate host fruit …

GJ Ragland, K Almskaar, KL Vertacnik… - Molecular …, 2015 - Wiley Online Library
Host race formation, the establishment of new populations using novel resources, is a major
hypothesized mechanism of ecological speciation, especially in plant‐feeding insects. The …

Transcriptional regulatory networks in Arabidopsis thaliana during single and combined stresses

P Barah, ND Jayavelu, R Sowdhamini… - Nucleic acids …, 2016 - academic.oup.com
Differentially evolved responses to various stress conditions in plants are controlled by
complex regulatory circuits of transcriptional activators, and repressors, such as transcription …

Zebrafish models for personalized psychiatry: Insights from individual, strain and sex differences, and modeling gene x environment interactions

AD Volgin, OA Yakovlev, KA Demin… - Journal of …, 2019 - Wiley Online Library
Currently becoming widely recognized, personalized psychiatry focuses on unique
physiological and genetic profiles of patients to best tailor their therapy. However, the role of …

Cis-acting variation is common across regulatory layers but is often buffered during embryonic development

S Floc'Hlay, ES Wong, B Zhao, RR Viales… - Genome …, 2021 - genome.cshlp.org
Precise patterns of gene expression are driven by interactions between transcription factors,
regulatory DNA sequences, and chromatin. How DNA mutations affecting any one of these …

From genome to anatomy: The architecture and evolution of the skeletogenic gene regulatory network of sea urchins and other echinoderms

T Shashikant, JM Khor, CA Ettensohn - genesis, 2018 - Wiley Online Library
The skeletogenic gene regulatory network (GRN) of sea urchins and other echinoderms is
one of the most intensively studied transcriptional networks in any developing organism. As …