Introduction: Globally, the three main pathogens causing serious infections are
Haemophilus influenzae type b, Streptococcus pneumoniae and Neisseria meningitidis …

Background Streptococcus pneumoniae is responsible for approximately 1.6 million yearly
deaths worldwide. An up-to-date evidence base on the effects of pneumococcal conjugate …

Background Children account for a substantial proportion of cases and deaths from Ebola
virus disease. We aimed to assess the safety and immunogenicity of a two-dose …

Maintaining a practical perspective, Bioequivalence and Statistics in Clinical Pharmacology,
Second Edition explores statistics used in day-to-day clinical pharmacology work. The book …

Objective Prophylactic antipyretic use during pediatric vaccination is common. This study
assessed whether paracetamol or ibuprofen prophylaxis interfere with immune responses to …

Background Despite the use of 23-valent pneumococcal polysaccharide vaccine (PPV23) in
adults there is substantial morbidity and mortality in the elderly due to pneumococcal …

Despite the availability of effective vaccines, Streptococcus pneumoniae is still one of the
major infectious diseases causing substantial morbidity and mortality in children under 5 …

Meta-analysis can be especially useful for evaluation of vaccine safety, since individual
studies often have limited power to detect an increase in safety risk. To gain a perspective …

Este trabajo resume el marco de evidencias que sustenta el actual uso de las vacunas
antineumocócicas conjugadas en términos de seguridad, inmunogenicidad, eficacia y …

L'Health Technology Assessment (HTA) è riconosciuto come lo strumento principe per
bilanciare l'esigenza di raggiungere la più ampia accessibilità/copertura possibile al netto …