Routes of drug administration and the corresponding physicochemical characteristics of a
given route play significant roles in therapeutic efficacy and short term/long term biological …

Nano-drug delivery systems (NDDS) for colon-targeted drug delivery are an active area of
research on local diseases affecting the colon, such as ulcerative colitis, Crohn's disease …

The canonical Wnt pathway is one of the key cellular signaling cascades that regulates, via
the transcriptional co-activator β-catenin, numerous embryogenic developmental processes …

Oxidative stress is a key factor in the development of inflammatory diseases. Elimination of
reactive oxygen species (ROS) in the inflamed colon has been confirmed as an effective …

The use of non-steroidal anti-inflammatory drugs (NSAIDs) in inflammatory bowel diseases
(IBDs) are contradictory between their beneficial effect in alleviating inflammation, and …

Microparticles (MPs) with pH-responding macropores have recently proved their
significance for the delivery of vulnerable biomolecules for oral drug administration. The …

Colon-targeted drug delivery systems have garnered significant interest as potential
solutions for delivering various medications susceptible to acidic and catalytic degradation …

Increasing efforts have been focused on development of novel therapeutic approaches
based on a carrier mixed with polymeric microparticles (MPs) for promoting bioactive factors …

The reduction in the systemic toxicity along with high efficiency of local drug delivery for the
diseases of colon (crohn's, ulcerative colitis, bowel disease, colon cancer) can be achieved …

Probiotics are considered a promising alternative to antibiotics for Salmonella disease
control. However, probiotics fed to poultry and humans lose most of their activity in the …