Trace amines are endogenous compounds classically regarded as comprising β-
phenylethyalmine, p-tyramine, tryptamine, p-octopamine, and some of their metabolites …

Candidate gene× environment (G× E) interaction research tests the hypothesis that the
effects of some environmental variable (eg, childhood maltreatment) on some outcome …

Abstract Machine learning methods have been employed to make predictions in psychiatry
from genotypes, with the potential to bring improved prediction of outcomes in psychiatric …

The discovery in 2001 of a G protein-coupled receptor family, subsequently termed trace
amine-associated receptors (TAAR), triggered a resurgence of interest in so-called trace …

Genotype imputation is now an essential tool in the analysis of genome-wide association
scans. This technique allows geneticists to accurately evaluate the evidence for association …

Evidence that childhood adversities are risk factors for psychosis has accumulated rapidly.
Research into the mechanisms underlying these relationships has focused, productively, on …

Although we have studied schizophrenia as a major disease entity over the past century, its
causes and pathogenesis remain obscure. In this article, we critically review genetic and …

Severe mental illness (SMI) is a broad category that includes schizophrenia, bipolar
disorder, and severe depression. Both genetic disposition and environmental exposures …

This article introduces the reader to the genetics of schizophrenia: its background; the status
of a variety of genetic findings; new developments (which are many since the last review) 1; …

Abstract Background The UK Biobank is a unique resource for biomedical research, with
extensive phenotypic and genetic data on half a million adults from the general population …