Obesity-related glomerulopathy: clinical and pathologic characteristics and pathogenesis

VD D'Agati, A Chagnac, AP De Vries, M Levi… - Nature Reviews …, 2016 - nature.com
The prevalence of obesity-related glomerulopathy is increasing in parallel with the
worldwide obesity epidemic. Glomerular hypertrophy and adaptive focal segmental …

Epidemiology of chronic kidney disease in children

J Harambat, KJ van Stralen, JJ Kim, EJ Tizard - Pediatric nephrology, 2012 - Springer
In the past 30 years there have been major improvements in the care of children with chronic
kidney disease (CKD). However, most of the available epidemiological data stem from end …

Effect of fetal and child health on kidney development and long-term risk of hypertension and kidney disease

VA Luyckx, JF Bertram, BM Brenner, C Fall, WE Hoy… - The Lancet, 2013 - thelancet.com
Developmental programming of non-communicable diseases is now an established
paradigm. With respect to hypertension and chronic kidney disease, adverse events …

Birth weight, malnutrition and kidney-associated outcomes—a global concern

VA Luyckx, BM Brenner - Nature Reviews Nephrology, 2015 - nature.com
An adverse intrauterine environment is associated with an increased risk of elevated blood
pressure and kidney disease in later life. Many studies have focused on low birth weight …

Obesity‐related glomerulopathy: Current approaches and future perspectives

JI Martínez‐Montoro, E Morales… - Obesity …, 2022 - Wiley Online Library
Obesity‐related glomerulopathy (ORG) is a silent comorbidity which is increasing in
incidence as the obesity epidemic escalates. ORG is associated with serious health …

Obesity and chronic kidney disease

Z Jiang, Y Wang, X Zhao, H Cui… - American Journal …, 2023 - journals.physiology.org
The prevalence of obesity has increased dramatically during the past decades, which has
been a major health problem. Since 1975, the number of people with obesity worldwide has …

Low birthweight as a risk factor for non-communicable diseases in adults

ME Bianchi, JM Restrepo - Frontiers in medicine, 2022 - frontiersin.org
According to studies undertaken over the past 40 years, low birthweight (LBW) is not only a
significant predictor of perinatal death and morbidity, but also increases the risk of chronic …

The long-term renal and cardiovascular consequences of prematurity

CL Abitbol, MM Rodriguez - Nature Reviews Nephrology, 2012 - nature.com
Infants born prematurely at< 37 weeks' gestation account for over 80% of infants weighing<
2,500 g at birth—low birth weight (LBW) infants. This designation remains the surrogate …

New pandemic: obesity and associated nephropathy

I Sharma, Y Liao, X Zheng, YS Kanwar - Frontiers in medicine, 2021 - frontiersin.org
Incidence of obesity related renal disorders have increased 10-folds in recent years. One of
the consequences of obesity is an increased glomerular filtration rate (GFR) that leads to the …

Clinical consequences of developmental programming of low nephron number

VA Luyckx, BM Brenner - The Anatomical Record, 2020 - Wiley Online Library
Nephron number in humans varies up to 13‐fold, likely reflecting the impact of multiple
factors on kidney development, including inherited body size and ethnicity, as well as …