Airway inflammation plays a central role in bronchiectasis. Protease–antiprotease balance is
crucial in bronchiectasis pathophysiology and increased presence of unopposed proteases …

Common variable immunodeficiency (CVID) is the most prevalent antibody deficiency,
characterized by remarkable genetic, immunological, and clinical heterogeneity. The …

Interstitial lung disease (ILD) is an important non-infectious complication in several primary
immune deficiencies. In common variable immune deficiency (CVID) it is associated with …

Common variable immunodeficiency disorders (CVID) are multi-system disorders where
target organ damage is mediated by infective, autoimmune and inflammatory processes …

Background Bronchiectasis is a major respiratory complication in patients with common
variable immunodeficiency (CVID) and is associated with recurrent pulmonary infections …

We suggest PLAID, APLAID, and FCAS3 have to be considered as different aspects of the
same underlying condition, because of our long‐term clinical and genetical experiences …

Bronchiectasis is a frequent complication of common variable immunodeficiency disorders
(CVID). In a cohort of patients with CVID, we sought to identify predictors of bronchiectasis …

Recurrent and life-threatening respiratory infections are nearly universal in patients with
primary immunodeficiency diseases (PIDD). Early recognition, aggressive treatment, and …

Common variable immunodeficiency (CVID) is the most clinically significant primary
antibody immunodeficiency recognized in adulthood. Previously published data have shown …

The broad and heterogeneous clinical spectrum that characterizes common variable
immunodeficiency (CVID) is associated with quite different disease course and prognosis …