Extracellular vesicles (EVs) are phospholipid bilayer membrane-enclosed structures
containing RNAs, proteins, lipids, metabolites, and other molecules, secreted by various …

Since the 2013 Nobel Prize was awarded for the discovery of vesicle trafficking, a subgroup
of nanovesicles called exosomes has been driving the research field to a new regime for …

Background Exosomes have emerged as a vital player in cell-cell communication; however,
whether airway epithelial cell (AEC)-generated exosomes participate in asthma …

Background Cystatin SN (CST1) and cystatin SA (CST2) are cysteine protease inhibitors that
protect against allergen, viral, and bacterial proteases. Cystatins are overexpressed in the …

Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by local
inflammation of the upper airways and is historically divided into 2 main phenotypes: CRS …

Intranasal administration offers a feasible, non-invasive method of delivering therapeutic
drugs to the brain, allowing therapeutic pharmaceuticals to be administered directly to the …

Background Nasal mucosa–derived exosomes (NMDEs) harbor immunodefensive proteins
and are capable of rapid interepithelial protein transfer. Objectives We sought to determine …

Extracellular vesicles (EVs) play an important role in the diagnosis and treatment of
diseases because of their rich molecular contents involved in intercellular communication …

We reported a microfluidic system for sorting of extracellular vesicles (EVs), which can
house DNAs, RNAs, lipids, proteins, and metabolites that are important in intercellular …

Renal ischemia-reperfusion injury (RIRI) is a complex disorder characterized by both
intrinsic damage to renal tubular epithelial cells and extrinsic inflammation mediated by …