Radioactive main group and rare earth metals for imaging and therapy

TI Kostelnik, C Orvig - Chemical reviews, 2018 - ACS Publications
Radiometals possess an exceptional breadth of decay properties and have been applied to
medicine with great success for several decades. The majority of current clinical use …

Advancement of metal compounds as therapeutic and diagnostic metallodrugs: Current frontiers and future perspectives

I Yousuf, M Bashir, F Arjmand, S Tabassum - Coordination Chemistry …, 2021 - Elsevier
Coordination compounds on account of distinctive features of metal ions that include
variable oxidation states, diverse range of geometries and coordination numbers …

Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of disease

TJ Wadas, EH Wong, GR Weisman… - Chemical …, 2010 - ACS Publications
Molecular imaging is the visualization, characterization, and measurement of biological
processes at the molecular and cellular levels in humans and other living systems …

Discovery and development of folic-acid-based receptor targeting for imaging and therapy of cancer and inflammatory diseases

PS Low, WA Henne… - Accounts of chemical …, 2008 - ACS Publications
In order to avoid the toxicities associated with prescription drug use today, we have explored
novel methods for delivering drugs selectively to pathologic cells, thereby avoiding the …

Folate receptor-mediated drug targeting: from therapeutics to diagnostics

AR Hilgenbrink, PS Low - Journal of pharmaceutical sciences, 2005 - Elsevier
Folate targeted drug delivery has emerged as an alternative therapy for the treatment and
imaging of many cancers and inflammatory diseases. Due to its small molecular size and …

[HTML][HTML] Medical applications and toxicities of gallium compounds

CR Chitambar - International journal of environmental research and …, 2010 - mdpi.com
Over the past two to three decades, gallium compounds have gained importance in the
fields of medicine and electronics. In clinical medicine, radioactive gallium and stable …

Targeted drug delivery via folate receptors

X Zhao, H Li, RJ Lee - Expert opinion on drug delivery, 2008 - Taylor & Francis
Targeted delivery via selective cellular markers can potentially increase the efficacy and
reduce the toxicity of therapeutic agents. The folate receptor (FR) has two glycosyl …

Tumor detection using folate receptor-targeted imaging agents

EI Sega, PS Low - Cancer and Metastasis reviews, 2008 - Springer
Folate receptors are up-regulated on a variety of human cancers, including cancers of the
breast, ovaries, endometrium, lungs, kidneys, colon, brain, and myeloid cells of …

A nuclear chocolate box: the periodic table of nuclear medicine

PJ Blower - Dalton Transactions, 2015 - pubs.rsc.org
Radioisotopes of elements from all parts of the periodic table find both clinical and research
applications in radionuclide molecular imaging and therapy (nuclear medicine). This article …

Small targeted cytotoxics: current state and promises from DNA‐encoded chemical libraries

N Krall, J Scheuermann, D Neri - … Chemie International Edition, 2013 - Wiley Online Library
The targeted delivery of potent cytotoxic agents has emerged as a promising strategy for the
treatment of cancer and other serious conditions. Traditionally, antibodies against markers of …