Radioactive main group and rare earth metals for imaging and therapy
TI Kostelnik, C Orvig - Chemical reviews, 2018 - ACS Publications
Radiometals possess an exceptional breadth of decay properties and have been applied to
medicine with great success for several decades. The majority of current clinical use …
medicine with great success for several decades. The majority of current clinical use …
Advancement of metal compounds as therapeutic and diagnostic metallodrugs: Current frontiers and future perspectives
Coordination compounds on account of distinctive features of metal ions that include
variable oxidation states, diverse range of geometries and coordination numbers …
variable oxidation states, diverse range of geometries and coordination numbers …
Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of disease
TJ Wadas, EH Wong, GR Weisman… - Chemical …, 2010 - ACS Publications
Molecular imaging is the visualization, characterization, and measurement of biological
processes at the molecular and cellular levels in humans and other living systems …
processes at the molecular and cellular levels in humans and other living systems …
Discovery and development of folic-acid-based receptor targeting for imaging and therapy of cancer and inflammatory diseases
PS Low, WA Henne… - Accounts of chemical …, 2008 - ACS Publications
In order to avoid the toxicities associated with prescription drug use today, we have explored
novel methods for delivering drugs selectively to pathologic cells, thereby avoiding the …
novel methods for delivering drugs selectively to pathologic cells, thereby avoiding the …
Folate receptor-mediated drug targeting: from therapeutics to diagnostics
AR Hilgenbrink, PS Low - Journal of pharmaceutical sciences, 2005 - Elsevier
Folate targeted drug delivery has emerged as an alternative therapy for the treatment and
imaging of many cancers and inflammatory diseases. Due to its small molecular size and …
imaging of many cancers and inflammatory diseases. Due to its small molecular size and …
[HTML][HTML] Medical applications and toxicities of gallium compounds
CR Chitambar - International journal of environmental research and …, 2010 - mdpi.com
Over the past two to three decades, gallium compounds have gained importance in the
fields of medicine and electronics. In clinical medicine, radioactive gallium and stable …
fields of medicine and electronics. In clinical medicine, radioactive gallium and stable …
Targeted drug delivery via folate receptors
Targeted delivery via selective cellular markers can potentially increase the efficacy and
reduce the toxicity of therapeutic agents. The folate receptor (FR) has two glycosyl …
reduce the toxicity of therapeutic agents. The folate receptor (FR) has two glycosyl …
Tumor detection using folate receptor-targeted imaging agents
EI Sega, PS Low - Cancer and Metastasis reviews, 2008 - Springer
Folate receptors are up-regulated on a variety of human cancers, including cancers of the
breast, ovaries, endometrium, lungs, kidneys, colon, brain, and myeloid cells of …
breast, ovaries, endometrium, lungs, kidneys, colon, brain, and myeloid cells of …
A nuclear chocolate box: the periodic table of nuclear medicine
PJ Blower - Dalton Transactions, 2015 - pubs.rsc.org
Radioisotopes of elements from all parts of the periodic table find both clinical and research
applications in radionuclide molecular imaging and therapy (nuclear medicine). This article …
applications in radionuclide molecular imaging and therapy (nuclear medicine). This article …
Small targeted cytotoxics: current state and promises from DNA‐encoded chemical libraries
N Krall, J Scheuermann, D Neri - … Chemie International Edition, 2013 - Wiley Online Library
The targeted delivery of potent cytotoxic agents has emerged as a promising strategy for the
treatment of cancer and other serious conditions. Traditionally, antibodies against markers of …
treatment of cancer and other serious conditions. Traditionally, antibodies against markers of …